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Robot-assisted laparoscopic repair of cesarean scar defect: a systematic review of clinical evidence

Gkegkes, I. D.; Psomiadou, V.; Minis, E.; Iavazzo, C. (Springer, 2022-11-27)

We aim to assess the available evidence concerning the robot-assisted repair of cesarean scar defect. A systematic PubMed and Scopus search was conducted. All databases were assessed up to May 23, 2022. Studies reporting ...
Portfolios in practice: Developing advancing practice within a musculoskeletal competency-based model

Langridge, N.; Welch, H.; Jones, D.; Small, C.; Lynch, G.; Ganatra, B. (Elsevier, 2022-11-13)

INTRODUCTION: The development of professional portfolios and the relevance of this within professional practice, competency and capability is gaining significant credibility in line with professional requirements. Nursing ...
A Rare Case of Open 3A VTB2W Periprosthetic Fracture around a Total Hip Arthroplasty

Selvaratnam, V.; Kassam, A. A.; Hubble, M. J. W. (Unknown, 2022-03-01)

INTRODUCTION: The incidence of periprosthetic fracture (PPF) around a total hip arthroplasty (THA) continues to increase with the rise of number of THA performed. We present a rare case of a 73-year-old man who sustained ...
EAES rapid guideline: systematic review, meta-analysis, GRADE assessment, and evidence-informed European recommendations on appendicitis in pregnancy

Adamina, M.; Andreou, A.; Arezzo, A.; Christogiannis, C.; Di Lorenzo, N.; Gioumidou, M.; Glavind, J.; Iavazzo, C.; Mavridis, D.; Muysoms, F. E.; Preda, D.; Smart, N. J.; Syropoulou, A.; Tzanis, AΑ; Van de Velde, M.; Vermeulen, J.; Antoniou, S. A. (Springer, 2022-12-01)

BACKGROUND: Clinical practice recommendations for the management of acute appendicitis in pregnancy are lacking. OBJECTIVE: To develop an evidence-informed, trustworthy guideline on the management of appendicitis in ...
Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism

Wakeling, M. N.; Owens, N. D. L.; Hopkinson, J. R.; Johnson, M. B.; Houghton, J. A. L.; Dastamani, A.; Flaxman, C. S.; Wyatt, R. C.; Hewat, T. I.; Hopkins, J. J.; Laver, T. W.; van Heugten, R.; Weedon, M. N.; De Franco, E.; Patel, K. A.; Ellard, S.; Morgan, N. G.; Cheesman, E.; Banerjee, I.; Hattersley, A. T.; Dunne, M. J.; Richardson, S. J.; Flanagan, S. E. (Nature, 2022-11-01)

Gene expression is tightly regulated, with many genes exhibiting cell-specific silencing when their protein product would disrupt normal cellular function(1). This silencing is largely controlled by non-coding elements, ...
UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2

Hanson, H.; Kulkarni, A.; Loong, L.; Kavanaugh, G.; Torr, B.; Allen, S.; Ahmed, M.; Antoniou, A. C.; Cleaver, R.; Dabir, T.; Evans, D. G.; Golightly, E.; Jewell, R.; Kohut, K.; Manchanda, R.; Murray, A.; Murray, J.; Ong, K. R.; Rosenthal, A. N.; Woodward, E. R.; Eccles, D. M.; Turnbull, C.; Tischkowitz, M.; Lalloo, F. (BMJ, 2022-11-21)

Germline pathogenic variants (GPVs) in the cancer predisposition genes BRCA1, BRCA2, MLH1, MSH2, MSH6, BRIP1, PALB2, RAD51D and RAD51C are identified in approximately 15% of patients with ovarian cancer (OC). While there ...
Personalised 3D Printed high tibial osteotomy achieves a high level of accuracy: 'IDEAL' preclinical stage evaluation of a novel patient specific system

MacLeod, A. R.; Mandalia, V. I.; Mathews, J. A.; Toms, A. D.; Gill, H. S. (Elsevier, 2022-10-01)

High tibial osteotomy (HTO) is an effective surgical treatment for isolated medial compartment knee osteoarthritis; however, widespread adoption is limited due to difficulty in achieving the planned correction, and patient ...
A narrative review of course evaluation methods for continuing professional development: The case of paediatric and neonatal acute-care in-service courses in low and lower-middle income countries: BEME Guide No. 76

Gifford, A.; Philemon, R.; Halbert, J.; Hothersall, E. J.; Inglis, R.; Hart, J.; Byrne-Davis, L.; Thirsk, J.; Gifford, H.; Howells, R.; Weetch, S.; Prentice, K.; Jackson, A.; Kirkpatrick, M. (Taylor and Francis Group, 2022-11-11)

BACKGROUND: Training a skilled healthcare workforce is an essential part in reaching the United Nations Sustainable Development Goal to end preventable deaths in children and neonates. The greatest burden of mortality lies ...
Marathon running and cell-cycle arrest biomarkers of acute kidney injury

Leckie, T.; Fitzpatrick, D.; Richardson, A. J.; Hunter, A.; Bains, S.; Grimaldi, R.; Galloway, R.; Forni, L. G.; Hodgson, L. E. (Elsevier, 2022-10-24)

OBJECTIVES: Endurance exercise is known to cause a rise in serum creatinine. It is not known to what extent this rise reflects renal stress and a potential acute kidney injury (AKI). Increases in Insulin Like Growth Factor ...
Author Correction: Clinically-relevant postzygotic mosaicism in parents and children with developmental disorders in trio exome sequencing data

Wright, C. F.; Prigmore, E.; Rajan, D.; Handsaker, J.; McRae, J.; Kaplanis, J.; Fitzgerald, T. W.; FitzPatrick, D. R.; Firth, H. V.; Hurles, M. E. (Nature, 2022-09-27)
Identifying type 1 and 2 diabetes in research datasets where classification biomarkers are unavailable: assessing the accuracy of published approaches

Thomas, N. J.; McGovern, A.; Young, K. G.; Sharp, S. A.; Weedon, M. N.; Hattersley, A. T.; Dennis, J.; Jones, A. G. (Elsevier, 2022-11-08)

OBJECTIVE: We aimed to compare the performance of approaches for classifying insulin treated diabetes within research datasets without measured classification biomarkers, evaluated against two independent biological ...
Photodynamic versus white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer: PHOTO RCT

Heer, R.; Lewis, R.; Duncan, A.; Penegar, S.; Vadiveloo, T.; Clark, E.; Yu, G.; Mariappan, P.; Cresswell, J.; McGrath, J.; N'Dow, J.; Nabi, G.; Mostafid, H.; Kelly, J.; Ramsay, C.; Lazarowicz, H.; Allan, A.; Breckons, M.; Campbell, K.; Campbell, L.; Feber, A.; McDonald, A.; Norrie, J.; Orozco-Leal, G.; Rice, S.; Tandogdu, Z.; Taylor, E.; Wilson, L.; Vale, L.; MacLennan, G.; Hall, E. (NIHR Journals Library, 2022-10-01)

BACKGROUND: Around 7500 people are diagnosed with non-muscle-invasive bladder cancer in the UK annually. Recurrence following transurethral resection of bladder tumour is common, and the intensive monitoring schedule ...
Safe prescribing in cancer patients during the COVID-19 pandemic: A new initiative from the UK Cancer Coronavirus Project (UKCCP) team

Appanna, N.; Patel, G.; Burke, E.; Burnett, A.; Clark, J.; Mew, R.; Khan, S.; Little, M.; Liu, J.; Panneerselvam, H.; Patel, V.; Platt, J.; Tilby, M.; Watts, I.; Harper-Wynne, C.; Lee, L. Y. (Wiley, 2022-12-01)
Corrigendum to Nomogram Predicting Bladder Cancer-specific Mortality After Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-invasive Bladder Cancer: Results of an International Consortium" [Eur Urol Focus 2021;7:1347-54]"

Mir, M. C.; Marchioni, M.; Zargar, H.; Zargar-Shoshtari, K.; Fairey, A. S.; Mertens, L. S.; Dinney, C. P.; Krabbe, L. M.; Cookson, M. S.; Jacobsen, N. E.; Griffin, J.; Montgomery, J. S.; Vasdev, N.; Yu, E. Y.; Xylinas, E.; McGrath, J. S.; Kassouf, W.; Dall'Era, M. A.; Sridhar, S. S.; Aning, J.; Shariat, S. F.; Wright, J. L.; Thorpe, A. C.; Morgan, T. M.; Holzbeierlein, J. M.; Bivalacqua, T. J.; North, S.; Barocas, D. A.; Lotan, Y.; Grivas, P.; Stephenson, A. J.; Shah, J. B.; van Rhijn, B. W.; Spiess, P. E.; Daneshmand, S.; Black, P. C. (Elsevier, 2022-02-15)
Sarcoidosis: Updates on therapeutic drug trials and novel treatment approaches

Obi, O. N.; Saketkoo, L. A.; Russell, A. M.; Baughman, R. P. (Frontiers Media, #VALUE!)

Sarcoidosis is a systemic granulomatous inflammatory disease of unknown etiology. It affects the lungs in over 90% of patients yet extra-pulmonary and multi-organ involvement is common. Spontaneous remission of disease ...
Safety of Same-Day Discharge Posterior Lumbar Decompression and/or Discectomy: An Observational Study Using Administrative Data From England

Gray, W. K.; Day, J.; Briggs, T. W. R.; Hutton, M. (Thieme, 2022-10-01)

STUDY DESIGN: Retrospective cohort study. OBJECTIVES: Same-day discharge is widely used in many surgical specialities. If carefully planned, it can improve patient outcomes whilst using resources efficiently. We aimed to ...
Importance of adopting standardized MANE transcripts in clinical reporting

Wright, C. F.; FitzPatrick, D. R.; Ware, J. S.; Rehm, H. L.; Firth, H. V. (Nature, 2022-11-28)
Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT

Jayne, D.; Walsh, M.; Merkel, P. A.; Peh, C. A.; Szpirt, W.; Puéchal, X.; Fujimoto, S.; Hawley, C.; Khalidi, N.; Jones, R.; Flossmann, O.; Wald, R.; Girard, L.; Levin, A.; Gregorini, G.; Harper, L.; Clark, W.; Pagnoux, C.; Specks, U.; Smyth, L.; Ito-Ihara, T.; de Zoysa, J.; Brezina, B.; Mazzetti, A.; McAlear, C. A.; Reidlinger, D.; Mehta, S.; Ives, N.; Brettell, E. A.; Jarrett, H.; Wheatley, K.; Broadhurst, E.; Casian, A.; Pusey, C. D. (NIHR Journals Library, 2022-09-01)

BACKGROUND: Anti-neutrophil cytoplasm antibody-associated vasculitis is a multisystem, autoimmune disease that causes organ failure and death. Physical removal of pathogenic autoantibodies by plasma exchange is recommended ...
FOSL2 truncating variants in the last exon cause a neurodevelopmental disorder with scalp and enamel defects

Cospain, A.; Rivera-Barahona, A.; Dumontet, E.; Gener, B.; Bailleul-Forestier, I.; Meyts, I.; Jouret, G.; Isidor, B.; Brewer, C.; Wuyts, W.; Moens, L.; Delafontaine, S.; Keung Lam, W. W.; Van Den Bogaert, K.; Boogaerts, A.; Scalais, E.; Besnard, T.; Cogne, B.; Guissard, C.; Rollier, P.; Carre, W.; Bouvet, R.; Tarte, K.; Gómez-Carmona, R.; Lapunzina, P.; Odent, S.; Faoucher, M.; Dubourg, C.; Ruiz-Pérez, V. L.; Devriendt, K.; Pasquier, L.; Pérez-Jurado, L. A. (Nature, #VALUE!)

PURPOSE: We aimed to investigate the molecular basis of a novel recognizable neurodevelopmental syndrome with scalp and enamel anomalies caused by truncating variants in the last exon of the gene FOSL2, encoding a subunit ...
World Health Organization (WHO) International Classification of Functioning, Disability and Health (ICF) Core Set Development for Interstitial Lung Disease

Saketkoo, L. A.; Escorpizo, R.; Varga, J.; Keen, K. J.; Fligelstone, K.; Birring, S. S.; Alexanderson, H.; Pettersson, H.; Chaudhry, H. A.; Poole, J. L.; Regardt, M.; LeSage, D.; Sarver, C.; Lanario, J.; Renzoni, E.; Scholand, M. B.; Lammi, M. R.; Kowal-Bielecka, O.; Distler, O.; Frech, T.; Shapiro, L.; Varju, C.; Volkmann, E. R.; Bernstein, E. J.; Drent, M.; Obi, O. N.; Patterson, K. C.; Russell, A. M. (Frontiers Media, #VALUE!)

Background: The World Health Organization (WHO) introduced the International Classification of Functioning, Disability, and Health (ICF) as a scientific method of disability data collection comprised of >1,200 categories ...

RD&E Research Repository: Recent submissions

Robot-assisted laparoscopic repair of cesarean scar defect: a systematic review of clinical evidence ﻿

Portfolios in practice: Developing advancing practice within a musculoskeletal competency-based model ﻿

A Rare Case of Open 3A VTB2W Periprosthetic Fracture around a Total Hip Arthroplasty ﻿

EAES rapid guideline: systematic review, meta-analysis, GRADE assessment, and evidence-informed European recommendations on appendicitis in pregnancy ﻿

Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism ﻿

UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2 ﻿

Personalised 3D Printed high tibial osteotomy achieves a high level of accuracy: 'IDEAL' preclinical stage evaluation of a novel patient specific system ﻿

A narrative review of course evaluation methods for continuing professional development: The case of paediatric and neonatal acute-care in-service courses in low and lower-middle income countries: BEME Guide No. 76 ﻿

Marathon running and cell-cycle arrest biomarkers of acute kidney injury ﻿

Author Correction: Clinically-relevant postzygotic mosaicism in parents and children with developmental disorders in trio exome sequencing data ﻿

Identifying type 1 and 2 diabetes in research datasets where classification biomarkers are unavailable: assessing the accuracy of published approaches ﻿

Photodynamic versus white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer: PHOTO RCT ﻿

Safe prescribing in cancer patients during the COVID-19 pandemic: A new initiative from the UK Cancer Coronavirus Project (UKCCP) team ﻿

Corrigendum to Nomogram Predicting Bladder Cancer-specific Mortality After Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-invasive Bladder Cancer: Results of an International Consortium" [Eur Urol Focus 2021;7:1347-54]" ﻿

Sarcoidosis: Updates on therapeutic drug trials and novel treatment approaches ﻿

Safety of Same-Day Discharge Posterior Lumbar Decompression and/or Discectomy: An Observational Study Using Administrative Data From England ﻿

Importance of adopting standardized MANE transcripts in clinical reporting ﻿

Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT ﻿

FOSL2 truncating variants in the last exon cause a neurodevelopmental disorder with scalp and enamel defects ﻿

World Health Organization (WHO) International Classification of Functioning, Disability and Health (ICF) Core Set Development for Interstitial Lung Disease ﻿

Robot-assisted laparoscopic repair of cesarean scar defect: a systematic review of clinical evidence

Portfolios in practice: Developing advancing practice within a musculoskeletal competency-based model

A Rare Case of Open 3A VTB2W Periprosthetic Fracture around a Total Hip Arthroplasty

EAES rapid guideline: systematic review, meta-analysis, GRADE assessment, and evidence-informed European recommendations on appendicitis in pregnancy

Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism

UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2

Personalised 3D Printed high tibial osteotomy achieves a high level of accuracy: 'IDEAL' preclinical stage evaluation of a novel patient specific system

A narrative review of course evaluation methods for continuing professional development: The case of paediatric and neonatal acute-care in-service courses in low and lower-middle income countries: BEME Guide No. 76

Marathon running and cell-cycle arrest biomarkers of acute kidney injury

Author Correction: Clinically-relevant postzygotic mosaicism in parents and children with developmental disorders in trio exome sequencing data

Identifying type 1 and 2 diabetes in research datasets where classification biomarkers are unavailable: assessing the accuracy of published approaches

Photodynamic versus white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer: PHOTO RCT

Safe prescribing in cancer patients during the COVID-19 pandemic: A new initiative from the UK Cancer Coronavirus Project (UKCCP) team

Corrigendum to Nomogram Predicting Bladder Cancer-specific Mortality After Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-invasive Bladder Cancer: Results of an International Consortium" [Eur Urol Focus 2021;7:1347-54]"

Sarcoidosis: Updates on therapeutic drug trials and novel treatment approaches

Safety of Same-Day Discharge Posterior Lumbar Decompression and/or Discectomy: An Observational Study Using Administrative Data From England

Importance of adopting standardized MANE transcripts in clinical reporting

Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT

FOSL2 truncating variants in the last exon cause a neurodevelopmental disorder with scalp and enamel defects

World Health Organization (WHO) International Classification of Functioning, Disability and Health (ICF) Core Set Development for Interstitial Lung Disease