Healing at skin graft donor sites dressed with chitosan

dc.citation.issue7
dc.citation.spage601-6
dc.citation.volume53
dc.contributor.authorStone, C. A.
dc.contributor.authorWright, H.
dc.contributor.authorClarke, T.
dc.contributor.authorPowell, R.
dc.contributor.authorDevaraj, V. S.
dc.date.accessioned2021-11-12T11:39:54Z
dc.date.available2021-11-12T11:39:54Z
dc.date.epub2000-09-23
dc.date.issued2000-09-23
dc.description.abstractChitosan is a derivative of chitin, extracted from the exoskeleton of lobsters, crabs and shrimps. As a semi-permeable biological dressing, it maintains a sterile wound exudate beneath a dry scab, preventing dehydration and contamination of the wound to optimise conditions for healing. In this study, evaluation of healing at split skin graft donor sites, dressed half with chitosan and half with a conventional dressing, showed that chitosan facilitated rapid wound re-epithelialisation and the regeneration of nerves within a vascular dermis. In addition, digital colour separation analysis of donor site scars demonstrated an earlier return to normal skin colour at chitosan-treated areas.
dc.description.admin-noteAccepted version
dc.description.noteRD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens
dc.identifier.doi10.1054/bjps.2000.3412
dc.identifier.journalBritish journal of plastic surgery
dc.identifier.pmid11000077
dc.identifier.urihttps://hdl.handle.net/11287/622192
dc.language.isoeng
dc.publisherElsevier
dc.relation.urlhttps://linkinghub.elsevier.com/retrieve/pii/S000712260093412X
dc.rightsCopyright 2000 The British Association of Plastic Surgeons.
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subject*Aged, 80 and over
dc.subjectAnti-Infective Agents/*pharmacology
dc.subjectBiocompatible Materials/pharmacology
dc.subject*Biological Dressings
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectChitin/analogs & derivatives/*pharmacology
dc.subjectChitosan
dc.subjectCicatrix/pathology
dc.subjectFemale
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectProspective Studies
dc.subjectSkin/pathology
dc.subjectSkin Pigmentation/drug effects
dc.subject*Skin Transplantation
dc.subjectTime Factors
dc.subjectWound Healing/*drug effects
dc.titleHealing at skin graft donor sites dressed with chitosan
dc.typeClinical Trial
dc.type.versionppublish
Files