Rapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity.

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Authors
Mifsud, K. R.
Saunderson, E. A.
Spiers, H.
Carter, S. D.
Trollope, A. F.
Mill, Jonathan
Reul, J. M H M
Journal
Neuroendocrinology
Type
Journal Article
Publisher
Karger
Rights
Archived with thanks to Neuroendocrinology
Although glucocorticoid receptors (GRs) in the hippocampus play a vital role in the regulation of physiological and behavioural responses to stress, the regulation of receptor expression remains unclear. This work investigates the molecular mechanisms underpinning stress-induced changes in hippocampal GR mRNA levels in vivo.
Citation
Rapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity. 2017;104(2):157-169. Epub 2016 Apr 8. Neuroendocrinology
Note