A novel case of a raised testosterone and LH in a young man.

dc.contributor.authorMcDonald, Timothy J.en
dc.contributor.authorPerry, Mandyen
dc.contributor.authorJones, Angus G.en
dc.contributor.authorDonohoe, Mollieen
dc.contributor.authorSalzmann, Maurice B.en
dc.contributor.authorO'Connor, John D.en
dc.date.accessioned2016-08-30T09:22:25Z
dc.date.available2016-08-30T09:22:25Z
dc.date.issued2011-10-09
dc.description.abstractA 19 year old male attended his GP with a history of "fluid retention", lack of libido and erectile dysfunction. He was found to have a high serum testosterone, and a raised luteinising hormone. After further investigations, the patient admitted to taking a supplement called ActivaTe Xtreme, obtained from an internet source, to address his low libido. ActivaTe Xtreme contains active ingredients which increase serum testosterone levels by several independent mechanisms that are not associated with luteinising hormone suppression. Urine analyses for synthetic anabolic steroids were negative, and urinary testosterone, epitestosterone and other androgens were normal. This biochemical pattern is not the same as that seen with anabolic steroids (i.e. raised testosterone, suppressed luteinising hormone and abnormal urine steroid profile). The issue of self medication with performance enhancing compounds needs to be carefully considered in order to avoid expensive and invasive investigations, missing an underlying pathology or misdiagnosing a patient. This case also raises the spectre of yet another "performance enhancing" product that may cause difficulty for those trying to ensure that sport remains on a "hormonally" equal basis.en
dc.description.fundingDRF-2010-03-72/Department of Health/United Kingdomen
dc.description.noteThis article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.en
dc.identifier.citationA novel case of a raised testosterone and LH in a young man. 2011, 412 (21-22):1999-2001 Clin. Chim. Actaen
dc.identifier.doi10.1016/j.cca.2011.06.028
dc.identifier.issn1873-3492
dc.identifier.journalClinica chimica acta; international journal of clinical chemistryen
dc.identifier.pmid21756889
dc.identifier.urihttp://hdl.handle.net/11287/619036
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/S0009898111003627en
dc.rightsArchived with thanks to Clinica chimica acta; international journal of clinical chemistryen
dc.subjectWessex Classification Subject Headings::Endocrinologyen
dc.titleA novel case of a raised testosterone and LH in a young man.en
dc.typeCase Reporten
dc.type.versionPublisheden
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