Show simple item record

dc.contributor.authorJordan, A. N.
dc.contributor.authorAnning, C.
dc.contributor.authorWilkes, L.
dc.contributor.authorBall, C.
dc.contributor.authorPamphilon, N.
dc.contributor.authorClark, C. E.
dc.contributor.authorBellenger, N. G.
dc.contributor.authorShore, A. C.
dc.contributor.authorSharp, A. S. P.
dc.contributor.authorValderas, J. M.
dc.date.accessioned2022-04-21T09:39:56Z
dc.date.available2022-04-21T09:39:56Z
dc.date.issued2022-03-04
dc.identifier.citationHealth Qual Life Outcomes. 2022 Mar 4;20(1):39. doi: 10.1186/s12955-022-01943-9.
dc.identifier.pmid35246164
dc.identifier.doi10.1186/s12955-022-01943-9
dc.identifier.urihttps://rde.dspace-express.com/handle/11287/622434
dc.description.abstractBACKGROUND: Hypertension is a highly prevalent condition, with optimal treatment to BP targets conferring significant gains in terms of cardiovascular outcomes. Understanding why some patients do not achieve BP targets would be enhanced through greater understanding of their health-related quality of life (HRQoL). However, the only English language disease-specific instruments for measurement of HRQoL in hypertension have not been validated in accordance with accepted standards. It is proposed that the Spanish MINICHAL instrument for the assessment of HRQoL in hypertension could be translated, adapted and validated for use in the United Kingdom. The aim of the study was therefore to complete this process. METHODS: The MINICHAL authors were contacted and the original instrument obtained. This was then translated into English by two independent English-speakers, with these versions then reconciled, before back-translation and subsequent production of a 2nd reconciled version. Thereafter, a final version was produced after cognitive debriefing, for administration and psychometric analysis in the target population of patients living in the Exeter area (Southwest UK) aged 18-80 years with treatment-naïve grade II-III hypertension, before, during and after 18 weeks' intensive treatment. RESULTS: The English-language instrument was administered to 30 individuals (median age: 58.5 years, 53% male). Psychometric analysis demonstrated a floor effect, though no ceiling effect. Internal consistency for both state of mind (StM) and somatic manifestations (SM) dimensions of the instrument were acceptable (Cronbach's alpha = 0.81 and 0.75), as was test-retest reliability (ICC = 0.717 and 0.961) and construct validity, which was measured through co-administration with the EQ-5D-5L and Bulpitt-Fletcher instruments. No significant associations were found between scores and patient characteristics known to affect HRQoL. The EQ-5D-5L instrument found an improvement in HRQoL following treatment, with the StM and SM dimensions of the English language MINICHAL trending to support this (d = 0.32 and 0.02 respectively). CONCLUSIONS: The present study details the successful English translation and validation of the MINICHAL instrument for use in individuals with hypertension. The data reported also supports an improvement in HRQoL with rapid treatment of grade II-III hypertension, a strategy which has been recommended by contemporaneous European guidelines. Trial registration ISRCTN registry number: 57475376 (assigned 25/06/2015).
dc.language.isoeng
dc.publisherBioMed Central
dc.relation.urlhttps://hqlo.biomedcentral.com/articles/10.1186/s12955-022-01943-9
dc.rights© 2022. The Author(s).
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectCross-Cultural Comparison
dc.subjectFemale
dc.subjectHumans
dc.subject*Language
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPsychometrics/methods
dc.subject*Quality of Life/psychology
dc.subjectReproducibility of Results
dc.subjectSurveys and Questionnaires
dc.subjectUnited Kingdom
dc.subjectYoung Adult
dc.subjectAdaptation
dc.subjectHypertension
dc.subjectMinichal
dc.subjectValidation
dc.titleCross-cultural adaptation of the Spanish MINICHAL instrument into English for use in the United Kingdom
dc.typeJournal Article
dc.identifier.journalHealth and quality of life outcomes
dc.identifier.pmcidPMC8895672
dc.description.noteThe article is available via Open Access. Click on the 'Additional link' above to access the full-text.
dc.type.versionepublish
dc.description.admin-notePublished version, accepted version
dc.date.epub2022-03-06
dc.citation.volume20
dc.citation.issue1
dc.citation.spage39


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

© 2022. The Author(s).
Except where otherwise noted, this item's license is described as © 2022. The Author(s).