Show simple item record

dc.contributor.authorClark, C. E.
dc.contributor.authorCampbell, J. L.
dc.contributor.authorPowell, R. J.
dc.date.accessioned2021-11-12T11:42:03Z
dc.date.available2021-11-12T11:42:03Z
dc.date.issued2007-04-26
dc.identifier.pmid17460712
dc.identifier.doi10.1038/sj.jhh.1002209
dc.identifier.urihttps://rde.dspace-express.com/handle/11287/622226
dc.description.abstractObjectives of this study were to measure the prevalence of a difference in blood pressure (BP) between arms and determine whether a difference is associated with increased risk of cardiovascular events or death. A prospective cohort study of 247 patients with hypertension was undertaken in one rural general practice in England. The main outcome measures were mean difference in BP between arms and new episodes of myocardial infarction, cerebrovascular event, onset of angina or peripheral vascular disease or death. A total of 57/247 (23%) patients had a mean difference in systolic BP between arms of >or=10 mm Hg and 8/247 (3%) had a mean difference of >or=20 mm Hg. A total of 15/247 (6%) patients had a mean difference in diastolic BP between arms of >or=10 mm Hg. Survival analysis after 4.7 years (range 3.3-5.9) showed a shorter mean survival time without event or death for patients with a difference in systolic BP of >or=10 mm Hg compared with a difference of <10 mm Hg (3.7 (95% confidence interval, 3.2-4.2) versus 4.8 (4.6-5.1) years; P<0.001; hazard ratio 2.5 (1.5-4.2), P=0.001). Difference in systolic BP of >or=10 mm Hg between arms is common in this primary care population and is associated with a shorter survival time to death or new cardiovascular event. Detection of a difference between arms may identify hypertensive patients at increased risk of cardiovascular events. Such an approach would allow more effective targeting of resources in primary prevention strategies.
dc.language.isoeng
dc.publisherNature
dc.relation.urlhttps://doi.org/10.1038/sj.jhh.1002209
dc.rightsCopyright © 2007, Nature Publishing Group
dc.subjectAged
dc.subject*Blood Pressure
dc.subjectCardiovascular Diseases/mortality
dc.subjectCohort Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectHypertension/*mortality/*physiopathology
dc.subjectMale
dc.subjectPrimary Health Care
dc.subjectProspective Studies
dc.titleThe interarm blood pressure difference as predictor of cardiovascular events in patients with hypertension in primary care: cohort study
dc.typeJournal Article
dc.identifier.journalJournal of human hypertension
dc.description.noteNot held
dc.type.versionppublish
dc.description.admin-noteaccepted version (12 month embargo), submitted version
dc.date.epub2007-04-27
dc.citation.volume21
dc.citation.issue8
dc.citation.spage633-8


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record