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    Field-testing and validation in a primary care setting of a point-of-care test for C-reactive protein

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    URI
    https://rde.dspace-express.com/handle/11287/622204
    Author
    Seamark, D. A.
    Backhouse, S. N.
    Powell, R.
    Date
    2003-03-29
    Journal
    Annals of clinical biochemistry
    Type
    Journal Article
    Publisher
    Sage
    DOI
    10.1258/000456303763046139
    Rights
    Copyright © 2021 by Association for Clinical Biochemistry and Laboratory Medicine
    Metadata
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    Abstract
    BACKGROUND: Use of point-of-care testing (POCT) in primary care has increased. There is a need for high-quality field evaluation of POCT before deployment can be considered. METHOD: A POCT system for C-reactive protein was evaluated in a routine general practice setting. The standard laboratory method was a dry slide method based in a routine hospital laboratory. RESULTS: Scatterplots for both venous and capillary blood POCT system results versus the standard laboratory assay produced correlation coefficients of greater than 0.96. Bland-Altman plots indicated that 95% of venous and capillary POCT results fell within +/-10 mg/L of the mean value with no clinically significant difference from laboratory results. CONCLUSIONS: The POCT system performed reliably in a routine general practice setting with satisfactory performance against an accepted laboratory method.
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    The article is available via Open Access. Click on the 'Additional link' above to access the full-text.
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