Field-testing and validation in a primary care setting of a point-of-care test for C-reactive protein

No Thumbnail Available
Authors
Seamark, D. A.
Backhouse, S. N.
Powell, R.
Journal
Annals of clinical biochemistry
Type
Journal Article
Publisher
Sage
Rights
Copyright © 2021 by Association for Clinical Biochemistry and Laboratory Medicine
BACKGROUND: Use of point-of-care testing (POCT) in primary care has increased. There is a need for high-quality field evaluation of POCT before deployment can be considered. METHOD: A POCT system for C-reactive protein was evaluated in a routine general practice setting. The standard laboratory method was a dry slide method based in a routine hospital laboratory. RESULTS: Scatterplots for both venous and capillary blood POCT system results versus the standard laboratory assay produced correlation coefficients of greater than 0.96. Bland-Altman plots indicated that 95% of venous and capillary POCT results fell within +/-10 mg/L of the mean value with no clinically significant difference from laboratory results. CONCLUSIONS: The POCT system performed reliably in a routine general practice setting with satisfactory performance against an accepted laboratory method.
Citation
Publisher URL
Note
The article is available via Open Access. Click on the 'Additional link' above to access the full-text.