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    Healing at skin graft donor sites dressed with chitosan

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    URI
    https://rde.dspace-express.com/handle/11287/622192
    Author
    Stone, C. A.
    Wright, H.
    Clarke, T.
    Powell, R.
    Devaraj, V. S.
    Date
    2000-09-23
    Journal
    British journal of plastic surgery
    Type
    Clinical Trial
    Publisher
    Elsevier
    DOI
    10.1054/bjps.2000.3412
    Rights
    Copyright 2000 The British Association of Plastic Surgeons.
    Metadata
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    Abstract
    Chitosan is a derivative of chitin, extracted from the exoskeleton of lobsters, crabs and shrimps. As a semi-permeable biological dressing, it maintains a sterile wound exudate beneath a dry scab, preventing dehydration and contamination of the wound to optimise conditions for healing. In this study, evaluation of healing at split skin graft donor sites, dressed half with chitosan and half with a conventional dressing, showed that chitosan facilitated rapid wound re-epithelialisation and the regeneration of nerves within a vascular dermis. In addition, digital colour separation analysis of donor site scars demonstrated an earlier return to normal skin colour at chitosan-treated areas.
    Publisher URL
    https://linkinghub.elsevier.com/retrieve/pii/S000712260093412X
    Note
    RD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens
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    • Plastic & Reconstructive Surgery
    • pre-2014 RD&E publications

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