Show simple item record

dc.contributor.authorJackson, John
dc.contributor.authorWalker, Eleanor
dc.contributor.authorBethune, Robert
dc.contributor.authorBracey, Tim
dc.contributor.authorMason, Chris
dc.contributor.authorMandalia, Trupti
dc.identifier.citationJackson, J. et al. (2020) 'Extramammary Borderline Phyllodes Tumor Presenting as an Umbilical Mass.', International journal of surgical pathology, p. 1066896920981632. doi: 10.1177/1066896920981632.
dc.description.abstractPhyllodes tumors (PTs) represent a spectrum of rare, fibroepithelial neoplasms of the breast, which can be subcategorized as benign, borderline, or malignant based on their histological appearance. Accessory breast tissue may present anywhere along the embryological mammary ridge, and at distant locations as aberrant breast tissue. We present the case of a 56-year-old lady with an umbilical mass, thought to represent a strangulated hernia. Sections showed a fibroepithelial tumor with leaf-like ducts, conspicuous mitotic activity (up to 8 per 10 high-power fields), and focal infiltration into fat. Immunohistochemical studies showed diffuse positivity of epithelial cells for estrogen receptor, mammaglobin, GCDFP-15, and CK7. These findings were consistent with a borderline PT. This is the first case report of PT presenting as an umbilical mass, and the first extramammary borderline PT described.
dc.rightsCopyright © 2021, © SAGE Publications
dc.subjectaccessory breast tissue
dc.subjectphyllodes tumor
dc.titleExtramammary Borderline Phyllodes Tumor Presenting as an Umbilical Mass.
dc.typeJournal Article
dc.identifier.journalInternational journal of surgical pathology
dc.description.noteRD&E staff can access the full-text of this article by clicking on the 'Additional Link' above and logging in with NHS OpenAthens if prompted.
dc.description.admin-notePublished version, accepted version

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record