Extramammary Borderline Phyllodes Tumor Presenting as an Umbilical Mass.

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Authors
Jackson, John
Walker, Eleanor
Bethune, Robert
Bracey, Tim
Mason, Chris
Mandalia, Trupti
Journal
International journal of surgical pathology
Type
Journal Article
Publisher
SAGE
Rights
Copyright © 2021, © SAGE Publications
Phyllodes tumors (PTs) represent a spectrum of rare, fibroepithelial neoplasms of the breast, which can be subcategorized as benign, borderline, or malignant based on their histological appearance. Accessory breast tissue may present anywhere along the embryological mammary ridge, and at distant locations as aberrant breast tissue. We present the case of a 56-year-old lady with an umbilical mass, thought to represent a strangulated hernia. Sections showed a fibroepithelial tumor with leaf-like ducts, conspicuous mitotic activity (up to 8 per 10 high-power fields), and focal infiltration into fat. Immunohistochemical studies showed diffuse positivity of epithelial cells for estrogen receptor, mammaglobin, GCDFP-15, and CK7. These findings were consistent with a borderline PT. This is the first case report of PT presenting as an umbilical mass, and the first extramammary borderline PT described.
Citation
Jackson, J. et al. (2020) 'Extramammary Borderline Phyllodes Tumor Presenting as an Umbilical Mass.', International journal of surgical pathology, p. 1066896920981632. doi: 10.1177/1066896920981632.
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