• Safe prescribing in cancer patients during the COVID-19 pandemic: A new initiative from the UK Cancer Coronavirus Project (UKCCP) team 

  Appanna, N.; Patel, G.; Burke, E.; Burnett, A.; Clark, J.; Mew, R.; Khan, S.; Little, M.; Liu, J.; Panneerselvam, H.; Patel, V.; Platt, J.; Tilby, M.; Watts, I.; Harper-Wynne, C.; Lee, L. Y. (Wiley, 2022-12-01)

• Infliximab and Tofacitinib Attenuate Neutralizing Antibody Responses Against SARS-CoV-2 Ancestral and Omicron Variants in Inflammatory Bowel Disease Patients Following 3 Doses of COVID-19 Vaccine 

  Liu, Z.; Alexander, J. L.; Lin, K. W.; Ahmad, T.; Pollock, K. M.; Powell, N. (Elsevier, 2022-10-19)

• Safety and Efficacy of the NVX-CoV2373 COVID-19 Vaccine at Completion of the Placebo-Controlled Phase of a Randomized Controlled Trial 

  Heath, P. T.; Galiza, E. P.; Baxter, D. N.; Boffito, M.; Browne, D.; Burns, F.; Chadwick, D. R.; Clark, R.; Cosgrove, C. A.; Galloway, J.; Goodman, A. L.; Heer, A.; Higham, A.; Iyengar, S.; Jeanes, C.; Kalra, P. A.; Kyriakidou, C.; Bradley, J. M.; Munthali, C.; Minassian, A. M.; McGill, F.; Moore, P.; Munsoor, I.; Nicholls, H.; Osanlou, O.; Packham, J.; Pretswell, C. H.; Francisco Ramos, A. S.; Saralaya, D.; Sheridan, R. P.; Smith, R.; Soiza, R. L.; Swift, P. A.; Thomson, E. C.; Turner, J.; Viljoen, M. E.; Fries, L.; Cho, I.; McKnight, I.; Glenn, G.; Rivers, E. J.; Robertson, A.; Alves, K.; Smith, K.; Toback, S. (Oxford University Press, 2022-10-10)

  BACKGROUND: The recombinant protein-based vaccine, NVX-CoV2373, demonstrated 89.7% efficacy against COVID-19 in a phase 3, randomized, observer-blinded, placebo-controlled trial in the United Kingdom. The protocol was ...

• COVID-19 pandemic interim Foundation Year 1 post and confidence in core skills and competencies: a longitudinal survey 

  Gatti, C. A.; Parker-Conway, K.; Okorie, M. (BMJ, 2022-11-02)

  OBJECTIVES: The interim Foundation Year 1 (FiY1) post was created in response to the COVID-19 pandemic to help bolster the workforce and manage increased clinical pressures. This study aimed to assess the impact of the ...

• The Impact of COVID Vaccination on Symptoms of Long COVID: An International Survey of People with Lived Experience of Long COVID 

  Strain, W. D.; Sherwood, O.; Banerjee, A.; Van der Togt, V.; Hishmeh, L.; Rossman, J. (MDPI, 2022-04-21)

  Long COVID is a multi-system syndrome following SARS-CoV-2 infection with persistent symptoms of at least 4 weeks, and frequently for several months. It has been suggested that there may be an autoimmune component. There ...

• The Impact of COVID Vaccination on Symptoms of Long COVID: An International Survey of People with Lived Experience of Long COVID 

  Strain, W. D.; Sherwood, O.; Banerjee, A.; Van der Togt, V.; Hishmeh, L.; Rossman, J. (MDPI, 2022-04-21)

  Long COVID is a multi-system syndrome following SARS-CoV-2 infection with persistent symptoms of at least 4 weeks, and frequently for several months. It has been suggested that there may be an autoimmune component. There ...

• The effect of the COVID-19 pandemic on severe asthma care in Europe: will care change for good? 

  Eger, K.; Paroczai, D.; Bacon, A.; Schleich, F.; Sergejeva, S.; Bourdin, A.; Vachier, I.; Zervas, E.; Katsoulis, K.; Papapetrou, D.; Kostikas, K.; Csoma, Z.; Heffler, E.; Canonica, G. W.; Grisle, I.; Bieksiene, K.; Palacionyte, J.; Ten Brinke, A.; Hashimoto, S.; Smeenk, Fwjm; Braunstahl, G. J.; van der Sar, S.; Mihălţan, F.; Nenasheva, N.; Peredelskaya, M.; Zvezdin, B.; Čekerevac, I.; Hromiš, S.; Ćupurdija, V.; Lazic, Z.; Milenkovic, B.; Dimic-Janjic, S.; Yasinska, V.; Dahlén, B.; Bossios, A.; Lazarinis, N.; Aronsson, D.; Egesten, A.; Munir, A. K. M.; Ahlbeck, L.; Janson, C.; Škrgat, S.; Edelbaher, N.; Leuppi, J.; Jaun, F.; Rüdiger, J.; Pavlov, N.; Gianella, P.; Fischer, R.; Charbonnier, F.; Chaudhuri, R.; Smith, S. J.; Doe, S.; Fawdon, M.; Masoli, M.; Heaney, L.; Haitchi, H. M.; Kurukulaaratchy, R.; Fulton, O.; Frankemölle, B.; Gibson, T.; Needham, K.; Howarth, P.; Djukanovic, R.; Bel, E.; Hyland, M. (European Respiratory Society, 2022-04-01)

  BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has put pressure on healthcare services, forcing the reorganisation of traditional care pathways. We investigated how physicians taking care of severe asthma ...

• Pregnancy and neonatal outcomes of COVID-19: The PAN-COVID study 

  Mullins, E.; Perry, A.; Banerjee, J.; Townson, J.; Grozeva, D.; Milton, R.; Kirby, N.; Playle, R.; Bourne, T.; Lees, C. (Elsevier, 2022-09-01)

  OBJECTIVE: To assess perinatal outcomes for pregnancies affected by suspected or confirmed SARS-CoV-2 infection. METHODS: Prospective, web-based registry. Pregnant women were invited to participate if they had suspected ...

• Nurses' strategies for overcoming barriers to fundamental nursing care in patients with COVID-19 caused by infection with the SARS-COV-2 virus: Results from the 'COVID-NURSE' survey 

  Sugg, H. V. R.; Richards, D. A.; Russell, A. M.; Burnett, S.; Cockcroft, E. J.; Thompson Coon, J.; Cruickshank, S.; Doris, F. E.; Hunt, H. A.; Iles-Smith, H.; Kent, M.; Logan, P. A.; Morgan, L. M.; Morley, N.; Rafferty, A. M.; Shepherd, M. H.; Singh, S. J.; Tooze, S. J.; Whear, R. (Wiley, 2022-04-25)

  AIMS: To identify strategies used by registered nurses and non-registered nursing care staff in overcoming barriers when providing fundamental nursing care for non-invasively ventilated inpatients with COVID-19. DESIGN: ...

• Infections in relapsed myeloma patients treated with isatuximab plus pomalidomide and dexamethasone during the COVID-19 pandemic: Initial results of a UK-wide real-world study 

  Djebbari, F.; Rampotas, A.; Vallance, G.; Panitsas, F.; Basker, N.; Sangha, G.; Salhan, B.; Karim, F.; Firas, A. K.; Gudger, A.; Ngu, L.; Poynton, M.; Lam, H. P. J.; Morgan, L.; Yang, L.; Young, J.; Walker, M.; Tsagkaraki, I.; Anderson, L.; Chauhan, S. R.; Maddams, R.; Soutar, R.; Triantafillou, M.; Prideaux, S.; Obeidalla, A.; Eyre, T. A.; Bygrave, C.; Basu, S.; Ramasamy, K. (American Society of Hematology, 2022-12-01)

  OBJECTIVES: There are no real-world data describing infection morbidity in relapsed/refractory myeloma (RRMM) patients treated with anti-CD38 isatuximab in combination with pomalidomide and dexamethasone (IsaPomDex). In ...

• Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial 

  Munro, A. P. S.; Feng, S.; Janani, L.; Cornelius, V.; Aley, P. K.; Babbage, G.; Baxter, D.; Bula, M.; Cathie, K.; Chatterjee, K.; Dodd, K.; Enever, Y.; Qureshi, E.; Goodman, A. L.; Green, C. A.; Harndahl, L.; Haughney, J.; Hicks, A.; van der Klaauw, A. A.; Kanji, N.; Libri, V.; Llewelyn, M. J.; McGregor, A. C.; Maallah, M.; Minassian, A. M.; Moore, P.; Mughal, M.; Mujadidi, Y. F.; Holliday, K.; Osanlou, O.; Osanlou, R.; Owens, D. R.; Pacurar, M.; Palfreeman, A.; Pan, D.; Rampling, T.; Regan, K.; Saich, S.; Bawa, T.; Saralaya, D.; Sharma, S.; Sheridan, R.; Thomson, E. C.; Todd, S.; Twelves, C.; Read, R. C.; Charlton, S.; Hallis, B.; Ramsay, M.; Andrews, N.; Lambe, T.; Nguyen-Van-Tam, J. S.; Snape, M. D.; Liu, X.; Faust, S. N. (Elsevier, 2022-05-14)

  BACKGROUND: Some high-income countries have deployed fourth doses of COVID-19 vaccines, but the clinical need, effectiveness, timing, and dose of a fourth dose remain uncertain. We aimed to investigate the safety, ...

• Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial 

  Liu, X.; Munro, A. P. S.; Feng, S.; Janani, L.; Aley, P. K.; Babbage, G.; Baxter, D.; Bula, M.; Cathie, K.; Chatterjee, K.; Dejnirattisai, W.; Dodd, K.; Enever, Y.; Qureshi, E.; Goodman, A. L.; Green, C. A.; Harndahl, L.; Haughney, J.; Hicks, A.; van der Klaauw, A. A.; Kwok, J.; Libri, V.; Llewelyn, M. J.; McGregor, A. C.; Minassian, A. M.; Moore, P.; Mughal, M.; Mujadidi, Y. F.; Holliday, K.; Osanlou, O.; Osanlou, R.; Owens, D. R.; Pacurar, M.; Palfreeman, A.; Pan, D.; Rampling, T.; Regan, K.; Saich, S.; Serafimova, T.; Saralaya, D.; Screaton, G. R.; Sharma, S.; Sheridan, R.; Sturdy, A.; Supasa, P.; Thomson, E. C.; Todd, S.; Twelves, C.; Read, R. C.; Charlton, S.; Hallis, B.; Ramsay, M.; Andrews, N.; Lambe, T.; Nguyen-Van-Tam, J. S.; Cornelius, V.; Snape, M. D.; Faust, S. N. (Elsevier, 2022-04-12)

  OBJECTIVES: To evaluate the persistence of immunogenicity three months after third dose boosters. METHODS: COV-BOOST is a multicentre, randomised, controlled, phase 2 trial of seven COVID-19 vaccines used as a third booster ...

• The benefits of virtual learning webinars to both low- and high-income countries 

  Ng, M.; Chamileke, N.; Mapulanga, V.; Campain, N.; Payne, S. (Wiley, 2022-04-01)

  The coronavirus disease 2019 (COVID-19) pandemic has brought about many changes in the relationships between high-income countries and partner organisations in low- or low-middle-income countries, such as predominate in ...

• 811 DELIRIUM IN COVID-19: COMMON AND CLINICALLY SIGNIFICANT: EXPERIENCES FROM THE NIGHTINGALE HOSPITAL EXETER 

  Reed, W; Fearnley, C; Tregarthen, A; Hubbard, J; Griffiths, J; Whitehead, T; Hacon, J; Anning, L (Oxford University Press, 2022-03-08)

  Delirium is an independent predictor of mortality in patients admitted with community-acquired pneumonia (Pieralli, 2014), but significance and incidence in Covid-19 infection has not been established. The Nightingale ...

• Providing information, care and support to IBD patients during the pandemic 

  Cairnes, V. (MA Healthcare, 2022-03-24)

  Vida Cairnes, Lead Inflammatory Bowel Disease (IBD) Nurse Specialist, Royal Devon and Exeter Hospital, and the Exeter IBD Specialist Nursing Team were runners-up in the Gastrointestinal/IBD Nurse of the Year category of ...

• P361 PREPARE-IBD: Physician Responses to disease Flares and Patient Adaptation in Relation to Events in Inflammatory Bowel Disease during the COVID-19 pandemic: A multicentre cohort analysis 

  Saifuddin, A; Kent, A; Mehta, S; Hicks, L; Gonzalez, H; Segal, J; Brooks, M; Subramanian, S; Bhala, N; Conley, T; Patel, K; Lamb, C; Walker, G; Kennedy, N; Sebastian, S; collaborators, PREPARE-IBD (Oxford University Press, 2022-01-21)

  The COVID-19 pandemic continues to pose complex problems across Europe and the world, with rising numbers of infections and the ongoing need for drastic public health interventions. This is difficult for patients with ...

• Pneumomediastinum in COVID-19: a phenotype of severe COVID-19 pneumonitis? The results of the United Kingdom (POETIC) survey 

  Melhorn, J.; Achaiah, A.; Conway, F. M.; Thompson, E. M. F.; Skyllberg, E. W.; Durrant, J.; Hasan, N. A.; Madani, Y.; Naran, P.; Vijayakumar, B.; Tate, M. J.; Trevelyan, G. E.; Zaki, I.; Doig, C. A.; Lynch, G.; Warwick, G.; Aujayeb, A.; Jackson, K. A.; Iftikhar, H.; Noble, J. H.; Ng, Aykc; Nugent, M.; Evans, P. J.; Hastings, R. A.; Bellenberg, H. R.; Lawrence, H.; Saville, R. L.; Johl, N. T.; Grey, A. N.; Ellis, H. C.; Chen, C.; Jones, T. L.; Maddekar, N.; Khan, S. L.; Muhammad, A. I.; Ghani, H.; Myint, Y. M. M.; Rafique, C.; Pippard, B. J.; Irving, B. R. H.; Ali, F.; Asimba, V. H.; Azam, A.; Barton, E. C.; Bhatnagar, M.; Blackburn, M. P.; Millington, K. J.; Budhram, N. J.; Bunclark, K. L.; Sapkal, T. P.; Dixon, G.; Harries, A. J. E.; Ijaz, M.; Karunanithi, V.; Naik, S.; Khan, M. A.; Savlani, K.; Kumar, V.; Gallego, B. L.; Mahdi, N. A.; Morgan, C.; Patel, N.; Rowlands, E. W.; Steward, M. S.; Thorley, R. S.; Wollerton, R. L.; Ullah, S.; Smith, D. M.; Lason, W.; Rostron, A. J.; Rahman, N. M.; Hallifax, R. J. (European Respiratory Society, 2022-02-10)

  BACKGROUND: There is an emerging understanding that coronavirus disease 2019 (COVID-19) is associated with increased incidence of pneumomediastinum. We aimed to determine its incidence among patients hospitalised with ...

• The impact of COVID-19 upon the delivery of exercise services within cystic fibrosis clinics in the United Kingdom 

  Tomlinson, O. W.; Saynor, Z. L.; Stevens, D.; Urquhart, D. S.; Williams, C. A. (Wiley Open Access, 2022-03-01)

  OBJECTIVES: The COVID-19 pandemic has resulted in unprecedent changes to clinical practice, and as the impact upon delivery of exercise services for people with cystic fibrosis (CF) in the United Kingdom was unknown, this ...

• Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab 

  Lin, S.; Kennedy, N. A.; Saifuddin, A.; Sandoval, D. M.; Reynolds, C. J.; Seoane, R. C.; Kottoor, S. H.; Pieper, F. P.; Lin, K. M.; Butler, D. K.; Chanchlani, N.; Nice, R.; Chee, D.; Bewshea, C.; Janjua, M.; McDonald, T. J.; Sebastian, S.; Alexander, J. L.; Constable, L.; Lee, J. C.; Murray, C. D.; Hart, A. L.; Irving, P. M.; Jones, G. R.; Kok, K. B.; Lamb, C. A.; Lees, C. W.; Altmann, D. M.; Boyton, R. J.; Goodhand, J. R.; Powell, N.; Ahmad, T. (Nature, 2022-03-16)

  Anti tumour necrosis factor (anti-TNF) drugs increase the risk of serious respiratory infection and impair protective immunity following pneumococcal and influenza vaccination. Here we report SARS-CoV-2 vaccine-induced ...

• COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study 

  Alexander, J. L.; Kennedy, N. A.; Ibraheim, H.; Anandabaskaran, S.; Saifuddin, A.; Castro Seoane, R.; Liu, Z.; Nice, R.; Bewshea, C.; D'Mello, A.; Constable, L.; Jones, G. R.; Balarajah, S.; Fiorentino, F.; Sebastian, S.; Irving, P. M.; Hicks, L. C.; Williams, H. R. T.; Kent, A. J.; Linger, R.; Parkes, M.; Kok, K.; Patel, K. V.; Teare, J. P.; Altmann, D. M.; Boyton, R. J.; Goodhand, J. R.; Hart, A. L.; Lees, C. W.; Ahmad, T.; Powell, N. (Elsevier, 2022-04-01)

  BACKGROUND: The effects that therapies for inflammatory bowel disease (IBD) have on immune responses to SARS-CoV-2 vaccination are not yet fully known. Therefore, we sought to determine whether COVID-19 vaccine-induced ...

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