The role of molecular genetics in the clinical management of sporadic medullary thyroid carcinoma: A systematic review
Fussey, Jonathan Mark
Smith, Joel Anthony
MetadataShow full item record
The significant variation in the clinical behaviour of sporadic medullary thyroid carcinoma (sMTC) causes uncertainty when planning the management of these patients. Several tumour genetic and epigenetic markers have been described, but their clinical usefulness remains unclear. The aim of this review was to evaluate the evidence for the use of molecular genetic and epigenetic profiles in the risk stratification and management of sMTC.