Show simple item record

dc.contributor.authorAdlington, Daniel
dc.contributor.authorMoore, Jason
dc.contributor.authorBingham, Coralie
dc.date.accessioned2019-11-11T11:51:31Z
dc.date.available2019-11-11T11:51:31Z
dc.date.issued2019-06
dc.identifier.citationAdlington D, Moore J, Bingham C. Remission of membranous nephropathy after treatment of localised prostate cancer. Case Reports in Nephrology and Dialysis. 2019;9:79–84en_US
dc.identifier.doi10.1159/000500948
dc.identifier.urihttps://rde.dspace-express.com/handle/11287/621114
dc.description.abstractMembranous nephropathy is a cause of the nephrotic syndrome in adults; it can be a primary or secondary process. Secondary causes include solid organ and lymphoid malignancies. Prostate cancer has been reported as the second most common causative malignancy. Remission of membranous nephropathy following treatment of metastatic prostate cancer is well established. In this case, we describe a patient with localised prostate cancer who developed severe nephrotic syndrome (urine protein creatinine ratio 1,616 mg/mmol and serum albumin 17 g/L) secondary to membranous nephropathy. The prostate cancer was deemed of low risk and so was being managed with active surveillance rather than medical treatment. Given the severity of the nephrotic syndrome a trial of androgen deprivation therapy with bicalutamide was agreed between the nephrology and urology teams. Full remission of the nephrotic syndrome was observed within 6 months of commencement of treatment (normalisation of serum albumin, non-nephrotic range urine protein creatinine ratio and resolution of oedema). The bicalutamide has been continued indefinitely.en_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.urlhttps://www.karger.com/Article/FullText/500948en_US
dc.rightsThis article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission.en_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectWessex Classification Subject Headings::Urology::Nephrology/Renal medicineen_US
dc.titleRemission of membranous nephropathy after treatment of localised prostate canceren_US
dc.typeCase Reporten_US
dc.identifier.journalCase Reports in Nephrology & Dialysisen_US
dc.description.noteThis article is freely available via Open Access. Click on the Publisher URL to access the full-text from the publisher's site.en_US
dc.type.versionPublisheden_US


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission.
Except where otherwise noted, this item's license is described as This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission.