2019 RD&E publications
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A summary list of all RD&E research outputs published or issued in 2019
Recent Submissions
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Reducing our carbon footprint and resource use on the Exeter Kidney Unit
(2019-07)Conference poster presented at the James Lovelock Centenary conference 'The Future of Global Systems Thinking', University of Exeter, 29th-31st July 2019. -
No health without planetary health
(2019-07) -
Pharmacist-led, video-stimulated feedback to reduce prescribing errors in doctors-in-training: a mixed methods evaluation
(British Pharmacological Society, 2019-07)AIM: To develop and evaluate a feasible, authentic pharmacist-led prescribing feedback intervention for doctors-in-training, to reduce prescribing errors. METHODS: This was a mixed methods study. Sixteen postgraduate ... -
Diagnostic accuracy and usability of home calprotectin testing
(European Crohn's and Colitis Organisation, 2019-01)Faecal calprotectin (FC) is a reliable and non-invasive stool biomarker that is useful in monitoring inflammation in patients with IBD. Testing is routinely performed in a laboratory by enzyme-linked immunosorbent assay ... -
Dosing, durability of haemoglobin response and safety of iron isomaltoside in outpatients with gastrointestinal diseases
(2019-06)Poster presented at the British Society of Gastroenterology 2019 Annual Conference, 17th-20 June 2019. -
Lip dose challenges in food allergy: current practice and diagnostic utility in the United Kingdom
(Elsevier, 2019-05-10) -
Fever and tachypnoea in a child
(BMJ, 2019-05-10) -
Systematic review and meta-analysis of incisional hernia post-reversal of ileostomy
(Springer, 2019-05-09)Incisional hernia following closure of loop ileostomy is a common problem. Assessment of the proportion of this complication is limited by small sample size and inconsistent reporting. The aim of this review was to provide ... -
Differences in outcome between patients readmitted to index vs non-index hospital trusts after colorectal resection
(Wiley, 2019-05-07)This study aimed to determine differences in outcome between patients readmitted to index vs non-index trusts after major surgery. -
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
(Nature, 2019-05)Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses ... -
"They've walked the walk": a systematic review of quantitative and qualitative evidence for parent-to-parent support for parents of babies in neonatal care
(Elsevier, 2019-04-18)The aim of this systematic review was to explore the effects and experiences of parent-to-parent support in neonatal intensive care from the perspectives of those giving, receiving, or implementing support. Electronic ... -
The use of adenosine stress perfusion cardiac magnetic resonance in determining incomplete revascularization post-coronary artery bypass grafting and the importance of anterior septal vessels
(European Society of Cardiology, 2019-04-10)Incomplete revascularization post-coronary artery bypass grafting (CABG) may occur in up to one quarter of patients,1 and meta-analyses suggest this is associated with poor outcomes.1,2 ESC guidelines now prioritize complete ... -
Renal nurses' lived experiences of discussions about sexuality
(Mark Allen Group, 2019-03)Renal teams focus predominantly on renal replacement therapy and physical symptom management, rather than psychological issues, such as mental health, body image or self-esteem. This study aims to increase understanding ... -
Disease progression and treatment response in data-driven subgroups of type 2 diabetes compared with models based on simple clinical features: an analysis using clinical trial data
(Elsevier, 2019-06)Research using data-driven cluster analysis has proposed five subgroups of diabetes with differences in diabetes progression and risk of complications. We aimed to compare the clinical utility of this subgroup-based approach ... -
Compound heterozygous Pkd1l1 variants in a family with two fetuses affected by heterotaxy and complex Chd
(Elsevier, 2019-04-23)Heterotaxy and congenital heart defects associated with pathogenic variants in the PKD1L1 gene (autosomal visceral heterotaxy type 8, MIM 617205) has been reported in only four individuals from three unrelated families. ... -
Periorbital necrotising fasciitis with underlying undiagnosed hepatitis C infection
(BMJ, 2019-04)We report the case of a 56-year-old man, previously well, who presented with a spontaneous right-sided periorbital necrotising soft tissue infection and subsequently found to have undiagnosed hepatitis C and liver cirrhosis. ... -
Single centre experience of bilateral gracilis flap perineal reconstruction following extra-levator abdominoperineal excision
(Wiley, 2019-04)A variety of tissue flaps have been described for the closure of perineal wounds following abdominoperineal excision of the rectum (APE) or exenteration for locally advanced/recurrent rectal cancer and salvage surgery for ... -
A specific CNOT1 mutation results in a novel syndrome of pancreatic agenesis and holoprosencephaly through impaired pancreatic and neurological development
(Cell Press, 2019-05)We report a recurrent CNOT1 de novo missense mutation, GenBank: NM_016284.4; c.1603C>T (p.Arg535Cys), resulting in a syndrome of pancreatic agenesis and abnormal forebrain development in three individuals and a similar ...
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