2019 RD&E publications
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A summary list of all RD&E research outputs published or issued in 2019
Recent Submissions
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Maximising access to thrombectomy services for stroke in England: A modelling study
(Sage, 2019-03)Both intravenous thrombolysis (IVT) and intra-arterial endovascular thrombectomy (ET) improve the outcome of patients with acute ischaemic stroke, with endovascular thrombectomy being an option for those patients with large ... -
Interventions for the treatment of Paget's disease of the vulva
(Wiley, 2019-06-05)This is an updated version of the original Cochrane Review published in Issue 10, 2013.Extramammary Paget's disease is a rare form of superficial skin cancer. The most common site of involvement is the vulva. It is seen ... -
Open versus laparoscopic mesh repair of primary unilateral uncomplicated inguinal hernia: a systematic review with meta-analysis and trial sequential analysis
(Springer, 2019-06-03)One standard repair technique for groin hernias does not exist. The objective of this study is to perform an update meta-analysis and trial sequential analysis to investigate if there is a difference in terms of recurrence ... -
Complicated disease and response to initial therapy predicts early surgery in paediatric Crohn's disease: results from the Porto Group GROWTH study
(Oxford Academic, 2019-06-03)The ability to predict risk for poor outcomes in Crohn's disease (CD) would enable early treatment intensification. We aimed to identify children with CD with complications at baseline and throughout the study period who ... -
In support of mesh for hernia repair
(Wiley, 2019-06) -
Ten-year results for a single-surgeon series of Scorpio non-restrictive geometry (NRG) posterior stabilised (PS) total knee replacement
(Springer, 2019-05)To report the long-term results for a single-surgeon consecutive series of Scorpio non-restrictive geometry (NRG) posterior stabilised (PS) total knee replacement (TKR). -
Wolcott-Rallison syndrome in Iran: a common cause of neonatal diabetes
(De Gruyter, 2019-06)Wolcott-Rallison syndrome is a rare autosomal recessive disorder characterized by neonatal/early-onset non-autoimmune insulin-dependent diabetes, multiple epiphyseal dysphasia and growth retardation. It is caused by mutations ... -
Genome-wide association study of microscopic colitis in the UK Biobank confirms immune-related pathogenesis
(Oxford Academic, 2019-05-24)The causes of microscopic colitis are currently poorly understood. Previous reports have found clinical associations with coeliac disease and genetic associations at the HLA locus on the ancestral 8.1 haplotype. We ... -
Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data
(Elsevier, 2019-08)There is a need to develop and validate biomarkers for treatment response and survival in tubo-ovarian high-grade serous carcinoma (HGSC). The chemotherapy response score (CRS) stratifies patients into complete/near-complete ... -
The relationships between symptoms, disability, perceived health and quality of life in amyotrophic lateral sclerosis/motor neuron disease
(Taylor & Francis, 2019-08)Objectives: Using the Wilson and Cleary model linking clinical variables to quality of life, we explored the associations between physical and psychological factors, disability, perceived health and quality of life in ... -
Investigation and treatment of pelvic vein reflux associated with varicose veins: current views and practice of 100 UK vascular specialists
(Sage, 2019-05-13)Management of pelvic vein disorders possibly contributing to leg varicose veins remains variable and controversial. This survey investigated practice in the UK. -
Arthroscopy of the symptomatic shoulder arthroplasty
(Elsevier, 2019-10)Assessment of a painful or stiff shoulder arthroplasty can be challenging. The cause of pain can sometimes be easily identified. However, some patients have normal levels of inflammatory markers, normal plain films, and ... -
Influence of hospital volume of procedures by year on the risk of revision of total hip and knee arthroplasties: a propensity score-matched cohort study
(MDPI, 2019-05-13)The volume of total hip (THA) and knee arthroplasties (TKA) performed in a hospital per year could be an influential factor on the revision of these procedures. The aims of this study were: To obtain comparable cohorts in ... -
Management of vulval lichen schlerosus: the role of the plastic surgeon
(Eplasty, 2019-04-24)A 45-year-old woman with vulval lichen sclerosus underwent excisional surgery with healing by secondary intent after several treatments of topical steroids failed. Recurrent disease and scarring led to a narrowed introitus, ... -
Reducing our carbon footprint and resource use on the Exeter Kidney Unit
(2019-07)Conference poster presented at the James Lovelock Centenary conference 'The Future of Global Systems Thinking', University of Exeter, 29th-31st July 2019. -
No health without planetary health
(2019-07) -
Pharmacist-led, video-stimulated feedback to reduce prescribing errors in doctors-in-training: a mixed methods evaluation
(British Pharmacological Society, 2019-07)AIM: To develop and evaluate a feasible, authentic pharmacist-led prescribing feedback intervention for doctors-in-training, to reduce prescribing errors. METHODS: This was a mixed methods study. Sixteen postgraduate ... -
Diagnostic accuracy and usability of home calprotectin testing
(European Crohn's and Colitis Organisation, 2019-01)Faecal calprotectin (FC) is a reliable and non-invasive stool biomarker that is useful in monitoring inflammation in patients with IBD. Testing is routinely performed in a laboratory by enzyme-linked immunosorbent assay ... -
Dosing, durability of haemoglobin response and safety of iron isomaltoside in outpatients with gastrointestinal diseases
(2019-06)Poster presented at the British Society of Gastroenterology 2019 Annual Conference, 17th-20 June 2019.
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