27 years of prenatal diagnosis for Huntington disease in the United Kingdom.

No Thumbnail Available
Authors
Turnpenny, Peter D.
Journal
Genetics in medicine : official journal of the American College of Medical Genetics
Type
Journal Article
Publisher
Nature
Rights
Archived with thanks to Genetics in medicine : official journal of the American College of Medical Genetics
There is little long-term, population-based data on uptake of prenatal diagnosis for Huntington disease (HD), a late-onset autosomal dominant neurodegenerative disorder, and the effect of the availability of preimplantation genetic diagnosis (PGD) on families' decisions about conventional prenatal diagnosis is not known. We report trends in prenatal diagnosis and preimplantation diagnosis for HD in the United Kingdom since services commenced.
Citation
PiƱa-Aguilar RE, Simpson SA, Alshatti A, et al. 27 years of prenatal diagnosis for Huntington disease in the United Kingdom. Genet Med. 2019;21(7):1639-1643. doi:10.1038/s41436-018-0367-z. Epub 2018 Dec 14
Note