Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis.

No Thumbnail Available
Authors
Chadi, S. A. [et al]
Daniels, Ian R.
Smart, Neil J.
Osborne, Melanie
Journal
The Lancet. Gastroenterology & Hepatology
Type
Journal Article
Publisher
Elsevier
Rights
Archived with thanks to The lancet. Gastroenterology & hepatology
In patients with rectal cancer who achieve clinical complete response after neoadjuvant chemoradiotherapy, watch and wait is a novel management strategy with potential to avoid major surgery. Study-level meta-analyses have reported wide variation in the proportion of patients with local regrowth. We did an individual participant data meta-analysis to investigate factors affecting occurrence of local regrowth.
Citation
Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis.2018 Dec;3(12):825-836 Lancet Gastroenterol Hepatol
Note