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    A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

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    URI
    http://hdl.handle.net/11287/620485
    Author
    Satsangi, J.
    Kennedy, Nicholas A.
    Mowat, C.
    Arnott, I.
    Keerie, C.
    Lewis, S.
    Ennis, H.
    Date
    2017-09
    Journal
    Efficacy and Mechanism Evaluation
    Type
    Technical report
    Publisher
    NIHR
    Metadata
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    Abstract
    Crohn’s disease (CD) is a chronic, relapsing, inflammatory bowel disease. Up to 65% of patients with CD require an operation to control the disease within 10 years. Both endoscopic and clinical recurrence is common within 2 years of operation, with re-operation rates cumulating at 5% of patients per year.
    Citation
    A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC). Efficacy and Mechanism Evaluation Volume:4 Issue:4 Sep 2017
    Publisher URL
    https://www.journalslibrary.nihr.ac.uk/eme/eme04040/
    Collections
    • 2017 RD&E publications
    • Gastroenterology

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