Behavioural changes in the rat following infection with varicella-zoster virus
Wallace, Christopher G
Fleetwood-Walker, S. M.
Dalziel, R. G.
Kelly, B. G.
Quinn, J. P.
Fiskerstrand, C. E.
Nash, A. A.
JournalJournal of General Virology
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Following the establishment of a chronic varicella-zoster virus infection in the rat, behavioural allodynia and hyperalgesia were observed in the injected, but not the contralateral hind limb up to 33 days post-infection. This model may prove useful in investigating mechanisms involved in the establishment of post-herpetic neuralgia.