Eligibility of real-life patients with COPD for inclusion in trials of inhaled long-acting bronchodilator therapy.
Halpin, David M
Randomized Controlled Trial
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Management guidelines of chronic obstructive pulmonary disease (COPD) are mainly based on results of randomised controlled trials (RCTs), but some authors have suggested limited representativeness of patients included in these trials. No previous studies have applied the full range of selection criteria to a broad COPD patient population in a real-life setting.