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dc.contributor.authorStride, A.en
dc.contributor.authorShepherd, Maggieen
dc.contributor.authorFrayling, T. M.en
dc.contributor.authorBulman, Mike Pen
dc.contributor.authorEllard, Sianen
dc.contributor.authorHattersley, Andrew T.en
dc.date.accessioned2016-09-02T11:04:50Z
dc.date.available2016-09-02T11:04:50Z
dc.date.issued2002-12
dc.identifier.citationIntrauterine hyperglycemia is associated with an earlier diagnosis of diabetes in HNF-1alpha gene mutation carriers. 2002, 25 (12):2287-91 Diabetes Careen
dc.identifier.issn0149-5992
dc.identifier.pmid12453975
dc.identifier.urihttp://hdl.handle.net/11287/619510
dc.description.abstractIn animals, experimentally induced maternal hyperglycemia during pregnancy results in hyperglycemic offspring. Similarly, Pima Indian offspring with mothers who are diabetic at the time of pregnancy have increased risk of early-onset diabetes. We hypothesized that exposure to hyperglycemia in utero would decrease the age at diagnosis of diabetes in patients with maturity-onset diabetes of the young (MODY) due to a mutation in the hepatocyte nuclear factor 1alpha (HNF-1alpha) gene.en
dc.language.isoenen
dc.publisherHighwireen
dc.relation.urlhttp://care.diabetesjournals.org/content/25/12/2287.longen
dc.rightsArchived with thanks to Diabetes careen
dc.subjectWessex Classification Subject Headings::Oncology. Pathology.::Geneticsen
dc.subjectWessex Classification Subject Headings::Endocrinology::Diabetesen
dc.titleIntrauterine hyperglycemia is associated with an earlier diagnosis of diabetes in HNF-1alpha gene mutation carriers.en
dc.typeResearch Support, Non-U.S. Gov'ten
dc.identifier.journalDiabetes careen
dc.description.noteRD&E staff can access the full-text of this article via OpenAthens. Click on the 'Additional Link' above to access the full-text and log in with NHS OpenAthens if prompted.en
dc.type.versionPublisheden


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