Stability and reproducibility of a single-sample urinary C-peptide/creatinine ratio and its correlation with 24-h urinary C-peptide.
McDonald, Timothy J.
Knight, Bridget A.
Salzmann, Maurice B.
Hattersley, Andrew T.
TypeResearch Support, Non-U.S. Gov't
RightsArchived with thanks to Clinical chemistry
MetadataShow full item record
C-peptide measurement in blood or 24-h urine samples provides useful information regarding endogenous insulin secretion, but problems related to the rapid degradation of C-peptide in blood and difficulty of 24-h urine collection have limited widespread routine clinical use of this test. We assessed the feasibility of measuring urinary C-peptide (UCP) with correction for creatinine concentration in single urine samples.