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    Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes.

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    URI
    http://hdl.handle.net/11287/619205
    Author
    McDonald, Timothy J.
    Colclough, K.
    Brown, R. S.
    Shields, Beverley
    Shepherd, Maggie
    Bingley, P.
    Williams, A. J.
    Hattersley, Andrew T.
    Ellard, Sian
    Date
    2011-09
    Journal
    Diabetic medicine : a journal of the British Diabetic Association
    Type
    Research Support, Non-U.S. Gov't
    Publisher
    Wiley
    DOI
    10.1111/j.1464-5491.2011.03287.x
    Rights
    Archived with thanks to Diabetic medicine : a journal of the British Diabetic Association
    Metadata
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    Abstract
    Maturity-onset diabetes of the young is a monogenic form of familial, young-onset diabetes. It is rare (∼1% diabetes) and may be misdiagnosed as Type 1 diabetes and inappropriately treated with insulin. Type 1 diabetes is characterized by the presence of islet autoantibodies, including glutamate decarboxylase (GAD) and islet antigen-2 (IA-2) antibodies. The prevalence of islet autoantibodies is unknown in maturity-onset diabetes of the young and may have the potential to differentiate this form of diabetes from Type 1 diabetes. The aim of this study was to determine the prevalence of GAD and IA-2 antibodies in patients with maturity-onset diabetes of the young and Type 1 diabetes.
    Citation
    Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes. 2011, 28 (9):1028-33 Diabet. Med.
    Publisher URL
    http://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2011.03287.x/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+3rd+September+2016+at+08.30+BST%2F+03%3A30+EDT%2F+15%3A30+SGT+for+5+hours+and+Sunday+4th+September+at+10%3A00+BST%2F+05%3A00+EST%2F+17%3A00+SGT+for+1+hour++for+essential+maintenance.+Apologies+for+the+inconvenience
    Note
    This article is freely available via Open Access. Click on the ‘Additional Link’ above to access the full-text from the publisher’s site.
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