High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes.
Author
McDonald, Timothy J.
Shields, Beverley
Lawry, J.
Owen, K.
Gloyn, A. L.
Ellard, Sian
Hattersley, Andrew T.
Date
2011-08Journal
Diabetes careType
Research Support, Non-U.S. Gov'tPublisher
HighwireDOI
10.2337/dc11-0323Rights
Archived with thanks to Diabetes careMetadata
Show full item recordAbstract
Maturity-onset diabetes of the young (MODY) as a result of mutations in hepatocyte nuclear factor 1-α (HNF1A) is often misdiagnosed as type 1 diabetes or type 2 diabetes. Recent work has shown that high-sensitivity C-reactive protein (hs-CRP) levels are lower in HNF1A-MODY than type 1 diabetes, type 2 diabetes, or glucokinase (GCK)-MODY. We aim to replicate these findings in larger numbers and other MODY subtypes.