Validation of a single-sample urinary C-peptide creatinine ratio as a reproducible alternative to serum C-peptide in patients with Type 2 diabetes.

Bowman, Pamela; McDonald, Timothy J.; Shields, Beverley; Knight, Bridget A.; Hattersley, Andrew T.

URI

http://hdl.handle.net/11287/619201

Author

Bowman, Pamela

McDonald, Timothy J.

Shields, Beverley

Knight, Bridget A.

Hattersley, Andrew T.

Date

2012-01

Journal

Diabetic medicine : a journal of the British Diabetic Association

Type

Comparative Study
Research Support, Non-U.S. Gov't
Validation Studies

Publisher

Wiley

DOI

10.1111/j.1464-5491.2011.03428.x

Rights

Archived with thanks to Diabetic medicine : a journal of the British Diabetic Association

Metadata

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Abstract

Serum C-peptide can be used in Type 2 diabetes as a measure of endogenous insulin secretion, but practicalities of collection limit its routine clinical use. Urine C-peptide creatinine ratio is a non-invasive alternative that is stable for at least 3 days at room temperature in boric acid preservative. We aimed to assess the utility of urine C-peptide creatinine ratio in individuals with Type 2 diabetes as an alternative to serum C-peptide.

Citation

Validation of a single-sample urinary C-peptide creatinine ratio as a reproducible alternative to serum C-peptide in patients with Type 2 diabetes. 2012, 29 (1):90-3 Diabet. Med.

Publisher URL

http://onlinelibrary.wiley.com/doi/10.1111/j.1464-5491.2011.03428.x/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+3rd+September+2016+at+08.30+BST/+03:30+EDT/+15:30+SGT+for+5+hours+and+Sunday+4th+September+at+10:00+BST/+05:00+EST/+17:00+SGT+for+1+hour++for+essential+maintenance.+Apologies+for+the+inconvenience

Note

This article is freely available via Open Access. Click on the ‘Additional Link’ above to access the full-text from the publisher’s site.