Urine C-peptide creatinine ratio is an alternative to stimulated serum C-peptide measurement in late-onset, insulin-treated diabetes.
Jones, Angus G.
McDonald, Timothy J.
Oram, Richard A.
Knight, Bridget A.
Hattersley, Andrew T.
JournalDiabetic medicine : a journal of the British Diabetic Association
Research Support, Non-U.S. Gov't
RightsArchived with thanks to Diabetic medicine : a journal of the British Diabetic Association
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Serum C-peptide measurement can assist clinical management of diabetes, but practicalities of collection limit widespread use. Urine C-peptide creatinine ratio may be a non-invasive practical alternative. The stability of C-peptide in urine allows outpatient or community testing. We aimed to assess how urine C-peptide creatinine ratio compared with serum C-peptide measurement during a mixed-meal tolerance test in individuals with late-onset, insulin-treated diabetes.