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    Acute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture.

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    URI
    http://hdl.handle.net/11287/619100
    Author
    Povlsen, B.
    Singh, Sarvpreet
    Date
    2014
    Journal
    BMJ case reports
    Type
    Case Report
    Publisher
    BMJ
    DOI
    10.1136/bcr-2013-203338
    Rights
    Archived with thanks to BMJ case reports
    Metadata
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    Abstract
    We report a case of acute (24 h) double flexor tendon rupture of the little finger after a single injection of collagenase clostridium histolyticum into a palmar Dupuytren's contracture cord which caused metacarpophalangeal joint contracture. Tendon surgery was performed 48 h postinjury with primary repair and standard rehabilitation but it resulted in poor active flexion due to adhesions. Previous papers have suggested that a needle inserted into the flexor tendon can be detected prior to the injection of collagenase by asking the patient to actively move the finger, but our test on an awake patient showed that when a 27-gauge needle was inserted into the flexor tendons through a thick palmar cord, the syringe did not move significantly when the patient moved the finger, and therefore this test does not minimise the risk of iatrogenic tendon injury when using collagenase (Xiapex) for Dupuytren's contracture.
    Citation
    Acute double flexor tendon ruptures following injection of collagenase clostridium histolyticum (Xiapex) for Dupuytren's contracture. 2014, 2014: BMJ Case Rep
    Publisher URL
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987618/
    Note
    This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from PMC.
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    • 2014 RD&E publications
    • General Trauma & Orthopaedics

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