Home urine C-peptide creatinine ratio (UCPCR) testing can identify type 2 and MODY in pediatric diabetes.
Author
Besser, R.
Shields, Beverley
Hammersley, S.
Colclough, Kevin
McDonald, Timothy J.
Gray, Z.
Heywood, J. J. N.
Barrett, T. G.
Hattersley, Andrew T.
Date
2013-05Journal
Pediatric diabetesType
Multicenter StudyResearch Support, Non-U.S. Gov't
Publisher
WileyDOI
10.1111/pedi.12008Rights
Archived with thanks to Pediatric diabetesMetadata
Show full item recordAbstract
Making the correct diabetes diagnosis in children is crucial for lifelong management. Type 2 diabetes and maturity onset diabetes of the young (MODY) are seen in the pediatric setting, and can be difficult to discriminate from type 1 diabetes. Postprandial urinary C-peptide creatinine ratio (UCPCR) is a non-invasive measure of endogenous insulin secretion that has not been tested as a diagnostic tool in children or in patients with diabetes duration <5 yr. We aimed to assess whether UCPCR can discriminate type 1 diabetes from MODY and type 2 in pediatric diabetes.