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    A novel case of a raised testosterone and LH in a young man.

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    URI
    http://hdl.handle.net/11287/619036
    Author
    McDonald, Timothy J.
    Perry, Mandy
    Jones, Angus G.
    Donohoe, Mollie
    Salzmann, Maurice B.
    O'Connor, John D.
    Date
    2011-10-09
    Journal
    Clinica chimica acta; international journal of clinical chemistry
    Type
    Case Report
    Publisher
    Elsevier
    DOI
    10.1016/j.cca.2011.06.028
    Rights
    Archived with thanks to Clinica chimica acta; international journal of clinical chemistry
    Metadata
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    Abstract
    A 19 year old male attended his GP with a history of "fluid retention", lack of libido and erectile dysfunction. He was found to have a high serum testosterone, and a raised luteinising hormone. After further investigations, the patient admitted to taking a supplement called ActivaTe Xtreme, obtained from an internet source, to address his low libido. ActivaTe Xtreme contains active ingredients which increase serum testosterone levels by several independent mechanisms that are not associated with luteinising hormone suppression. Urine analyses for synthetic anabolic steroids were negative, and urinary testosterone, epitestosterone and other androgens were normal. This biochemical pattern is not the same as that seen with anabolic steroids (i.e. raised testosterone, suppressed luteinising hormone and abnormal urine steroid profile). The issue of self medication with performance enhancing compounds needs to be carefully considered in order to avoid expensive and invasive investigations, missing an underlying pathology or misdiagnosing a patient. This case also raises the spectre of yet another "performance enhancing" product that may cause difficulty for those trying to ensure that sport remains on a "hormonally" equal basis.
    Citation
    A novel case of a raised testosterone and LH in a young man. 2011, 412 (21-22):1999-2001 Clin. Chim. Acta
    Publisher URL
    http://www.sciencedirect.com/science/article/pii/S0009898111003627
    Note
    This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.
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    • Exeter Clinical Laboratory International (Blood Sciences, Genetics, Cellular Pathology & Microbiology)
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