Insulin resistance is associated with lower acetylcholine-induced microvascular reactivity in nondiabetic women.
Pienaar, P. R.
Levitt, N. S.
Goedecke, J. H.
Gill, J. M. R.
Lambert, E. V.
JournalMetabolic syndrome and related disorders
Research Support, Non-U.S. Gov't
PublisherMary Ann Liebert
RightsArchived with thanks to Metabolic syndrome and related disorders
MetadataShow full item record
The association between insulin resistance and microvascular dysfunction is well established in obese individuals with type 2 diabetes. It is unclear whether this relationship is dependent on obesity and body fat in insulin-resistant persons. This study investigated acetylcholine (ACh)-induced microvascular reactivity in apparently healthy women (n=37, 20-45 years), with and without insulin resistance.