Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study.
Author
Shore, Angela
Colhoun, H M
Natali, A
Palombo, C
Östling, G
Aizawa, Kunihiko
Kennbäck, C
Casanova, Francesco
Persson, M
Gooding, Kim M.
Gates, Phillip E.
Khan, F
Looker, H C
Adams, F
Belch, J
Pinnoli, S
Venturi, E
Morizzo, C
Goncalves, I
Ladenvall, C
Nilsson, J
Date
2015-09Journal
Journal of internal medicineType
Journal ArticleResearch Support, Non-U.S. Gov't
Publisher
WileyDOI
10.1111/joim.12359Rights
Archived with thanks to Journal of internal medicineMetadata
Show full item recordAbstract
There is a need to develop and validate surrogate markers of cardiovascular disease (CVD) in subjects with diabetes. The macrovascular changes associated with diabetes include aggravated atherosclerosis, increased arterial stiffness and endothelial dysfunction. The aim of this study was to determine which of these factors is most strongly associated with clinically manifest cardiovascular events.