Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study.
Colhoun, H M
Gooding, Kim M.
Gates, Phillip E.
Looker, H C
JournalJournal of internal medicine
Research Support, Non-U.S. Gov't
RightsArchived with thanks to Journal of internal medicine
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There is a need to develop and validate surrogate markers of cardiovascular disease (CVD) in subjects with diabetes. The macrovascular changes associated with diabetes include aggravated atherosclerosis, increased arterial stiffness and endothelial dysfunction. The aim of this study was to determine which of these factors is most strongly associated with clinically manifest cardiovascular events.