• Login
    View Item 
    •   RD&E Research Repository Home
    • All RD&E publications by year
    • 2015 RD&E publications
    • View Item
    •   RD&E Research Repository Home
    • All RD&E publications by year
    • 2015 RD&E publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

    Thumbnail
    URI
    http://hdl.handle.net/11287/618031
    Author
    Goncalves, I.
    Bengtsson, E.
    Colhoun, H. M.
    Shore, Angela
    Palombo, C.
    Natali, A.
    Edsfeldt, A.
    Dunér, P.
    Fredrikson, G. N.
    Björkbacka, H.
    Östling, G.
    Aizawa, Kunihiko
    Casanova, Francesco
    Persson, M.
    Gooding, Kim
    Strain, David
    Khan, F.
    Looker, H. C.
    Adams, F.
    Belch, J.
    Pinnoli, S.
    Venturi, E.
    Kozakova, M.
    Gan, L.-M.
    Schnecke, V.
    Nilsson, J.
    Date
    2015-07
    Journal
    Arteriosclerosis, thrombosis, and vascular biology
    Type
    Journal Article
    Research Support, Non-U.S. Gov't
    Publisher
    American Heart Association
    DOI
    10.1161/ATVBAHA.115.305631
    Rights
    Archived with thanks to Arteriosclerosis, thrombosis, and vascular biology
    Metadata
    Show full item record
    Abstract
    Matrix metalloproteinases (MMPs) degrade extracellular matrix proteins and play important roles in development and tissue repair. They have also been shown to have both protective and pathogenic effects in atherosclerosis, and experimental studies have suggested that MMP-12 contributes to plaque growth and destabilization. The objective of this study was to investigate the associations between circulating MMPs, atherosclerosis burden, and incidence of cardiovascular disease with a particular focus on type 2 diabetes mellitus.
    Citation
    Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes. 2015, 35 (7):1723-31 Arterioscler. Thromb. Vasc. Biol.
    Publisher URL
    http://atvb.ahajournals.org/cgi/pmidlookup?view=long&pmid=25953645
    Note
    This article is freely available online. Click on the 'Additional Link' above to access the full-text via the publisher's site.
    Collections
    • 2015 RD&E publications
    • Cardiology
    • Honorary contracts publications
    • Stroke

    Browse

    All of RD&E Research RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2021  DuraSpace
    Contact Us | Send Feedback
    DSpace Express is a service operated by 
    Atmire NV