Measuring infliximab and adalimumab drug and antibodies in Crohn's disease and ulcerative colitis
Author
Perry, Mandy
McDonald, Timothy J.
Cudmore, Adrian
Ahmad, Tariq
Date
2015-11-02Journal
Clinical Laboratory InternationalType
Journal ArticlePublisher
Clinical Laboratory InternationalMetadata
Show full item recordAbstract
The anti-TNF therapies infliximab and adalimumab have revolutionized the treatment of inflammatory bowel disease, being very effective in many patients. Some patients experience problems such as loss of response, which is associated with production of antibodies to the therapy. Measuring trough drug and antibody concentrations may direct patient management in future.