Measuring infliximab and adalimumab drug and antibodies in Crohn's disease and ulcerative colitis
McDonald, Timothy J.
JournalClinical Laboratory International
PublisherClinical Laboratory International
MetadataShow full item record
The anti-TNF therapies infliximab and adalimumab have revolutionized the treatment of inflammatory bowel disease, being very effective in many patients. Some patients experience problems such as loss of response, which is associated with production of antibodies to the therapy. Measuring trough drug and antibody concentrations may direct patient management in future.