The Alpha-Defensin Immunoassay and Leukocyte Esterase Colorimetric Strip Test for the Diagnosis of Periprosthetic Infection: A Systematic Review and Meta-Analysis.
Wyatt, Michael C.
Beswick, A. D.
Kunutsor, S. K.
Wilson, Matthew J.
Whitehouse, M. R.
Blom, A. W.
JournalThe Journal of bone and joint surgery. American volume
PublisherJournal of Bone & Joint Surgery
RightsArchived with thanks to The Journal of Bone and Joint Surgery. American volume
MetadataShow full item record
Synovial biomarkers have recently been adopted as diagnostic tools for periprosthetic joint infection (PJI), but their utility is uncertain. The purpose of this systematic review and meta-analysis was to synthesize the evidence on the accuracy of the alpha-defensin immunoassay and leukocyte esterase colorimetric strip test for the diagnosis of PJI compared with the Musculoskeletal Infection Society diagnostic criteria.