The Alpha-Defensin Immunoassay and Leukocyte Esterase Colorimetric Strip Test for the Diagnosis of Periprosthetic Infection: A Systematic Review and Meta-Analysis.
Author
Wyatt, Michael C.
Beswick, A. D.
Kunutsor, S. K.
Wilson, Matthew J.
Whitehouse, M. R.
Blom, A. W.
Date
2016-06-15Journal
The Journal of bone and joint surgery. American volumeType
Journal ArticleMeta-Analysis
Systematic review
Publisher
Journal of Bone & Joint SurgeryDOI
10.2106/JBJS.15.01142Rights
Archived with thanks to The Journal of Bone and Joint Surgery. American volumeMetadata
Show full item recordAbstract
Synovial biomarkers have recently been adopted as diagnostic tools for periprosthetic joint infection (PJI), but their utility is uncertain. The purpose of this systematic review and meta-analysis was to synthesize the evidence on the accuracy of the alpha-defensin immunoassay and leukocyte esterase colorimetric strip test for the diagnosis of PJI compared with the Musculoskeletal Infection Society diagnostic criteria.