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    Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy.

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    URI
    http://hdl.handle.net/11287/609973
    Author
    Hunt, William T.
    Cameron, A.
    Craig, P.
    de Berker, D. A.
    Date
    2013-08-13
    Journal
    Clinical and experimental dermatology
    Type
    Journal Article
    Publisher
    Wiley
    DOI
    10.1111/ced.12149
    Rights
    Archived with thanks to Clinical and experimental dermatology
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    Abstract
    Multiple periungual Bowen disease [BD; also known as squamous cell carcinoma (SCC) in situ] is rare. The pathogenesis of the disease is linked to human papilloma virus, and in some instances to chronic immunosuppression. The usual management of periungual BD is by local excision, Mohs micrographic surgery or distal phalanx amputation. Our patient was offered radiotherapy in the hope of maximizing residual function and minimizing morbidity from treatment. A good response was seen at 2 months post-radiotherapy, but this was followed by relapses at 4 and 6 months post-radiotherapy. Persistent anonychia resulted in improved access to the involved skin, making topical therapy possible. Radiotherapy can be a valuable management approach for periungual SCC/BD in locations where amputation could result in substantial disability.
    Citation
    Multiple-digit periungual Bowen's disease: a novel treatment approach with radiotherapy. 2013, 38 (8):857-61 Clin. Exp. Dermatol.
    Publisher URL
    http://onlinelibrary.wiley.com/doi/10.1111/ced.12149/abstract;jsessionid=BA430228539DC6444C0846B32C5BCFF0.f04t04
    Note
    This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.
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