Rapid Down-Regulation of Glucocorticoid Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and microRNA Activity.
Mifsud, K. R.
Saunderson, E. A.
Carter, S. D.
Trollope, A. F.
Reul, J. M H M
RightsArchived with thanks to Neuroendocrinology
MetadataShow full item record
Although glucocorticoid receptors (GRs) in the hippocampus play a vital role in the regulation of physiological and behavioural responses to stress, the regulation of receptor expression remains unclear. This work investigates the molecular mechanisms underpinning stress-induced changes in hippocampal GR mRNA levels in vivo.