Allergy in total knee arthroplasty: a review of the facts.
JournalThe bone & joint journal
PublisherBritish Editorial Society of Bone and Joint Journal
RightsArchived with thanks to The bone & joint journal
MetadataShow full item record
We explored the literature surrounding whether allergy and hypersensitivity has a clinical basis for implant selection in total knee arthroplasty (TKA). In error, the terms hypersensitivity and allergy are often used synonymously. Although a relationship is present, we could not find any evidence of implant failure due to allergy. There is however increasing basic science that suggests a link between loosening and metal ion production. This is not an allergic response but is a potential problem. With a lack of evidence logically there can be no justification to use 'hypoallergenic' implants in patients who have pre-existing skin sensitivity to the metals used in TKA. Cite this article:Bone Joint J2016;98-B:437-41.