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Now showing items 1-10 of 14
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Psoriasis management: patient feedback and healthcare limitations
(SciTechnol, 2016-07-14)Background: Psoriasis is a lifelong, incurable, disfiguring skin disease. It has been associated with metabolic and psychological comorbidities and up to one third of patients developed psoriatic arthritis. The management ... -
Factors determining penetrance in familial atypical haemolytic uraemic syndrome
(BMJ, 2014-11-01)BACKGROUND: Inherited abnormalities of complement are found in approximately 60% of patients with atypical haemolytic uraemic syndrome (aHUS). Such abnormalities are not fully penetrant. In this study, we have estimated ... -
Are we seeing the effects of public awareness campaigns? A 10-year analysis of Breslow thickness at presentation of malignant melanoma in the South West of England
(Elsevier, 2014-03-01)INTRODUCTION: The last 20 years has seen a marked improvement in skin cancer awareness campaigns. We sought to establish whether this has affected the presenting Breslow thickness of malignant melanoma in the South West. ... -
Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature
(BMJ, 2015-11-02)OBJECTIVE: Clinicians predominantly use clinical features to differentiate type 1 from type 2 diabetes yet there are no evidence-based clinical criteria to aid classification of patients. Misclassification of diabetes is ... -
Pilot randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people “STOPCUTS”: study protocol
(BioMed Central, 2015-04-01)Skin tears are traumatic injuries occurring mostly on the extremities due to shearing and friction forces that separate the epidermis and the dermis from underlying tissues. They are common and occur mostly in older adults ... -
Learning neonatal intubation with a video laryngoscope
(Infant, 2015-05)Although increasing used in adult and paediatric populations, the use of video laryngoscopy in a neonatal setting has not been extensively researched. This article describes a study showing that intubation of a manikin ... -
A randomized controlled trial of postoperative analgesia following total knee replacement: transdermal Fentanyl patches versus patient controlled analgesia (PCA).
(Springer, 2015-08)This randomized controlled trial compared a standard patient controlled analgesic (PCA) regime with a transdermal and oral Fentanyl regime for post-operative pain management in patients undergoing total knee replacement. -
Assessing the accuracy of ultrasound estimation of gestational age during routine antenatal care in in vitro fertilization (IVF) pregnancies.
(Sage, 2018-02)In the UK an accurate gestational age is confirmed by ultrasound measured foetal crown rump length (CRL) at 11 + 2-14 + 1 weeks of gestation. The currently recommended Robinson and Fleming crown rump length reference chart ... -
The diagnostic accuracy of multiparametric MRI prior to biopsy in the detection of prostate cancer.
(Wiley, 2018-05-27)To determine the extent to which clinically significant prostate cancer (csPCa) can be detected in a routine NHS setting, in men with no previous biopsy, when mpMRI is introduced into the diagnostic pathway. This was ... -
Pilot parallel randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people: 'STOPCUTS'.
(BioMed Central, 2017-10-17)Skin tears are common in older adults and those taking steroids and warfarin. They are traumatic, often blunt injuries caused by oblique knocks to the extremities. The epidermis may separate from the dermis or both layers ...