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    Relapse after withdrawal from anti-TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta-analysis.

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    Open Access article (447.4Kb)
    URI
    http://hdl.handle.net/11287/600306
    Author
    Kennedy, N. A.
    Warner, B
    Johnston, E L
    Flanders, L
    Hendy, P
    Ding, N S
    Harris, R
    Fadra, A S
    Basquill, C
    Lamb, C A
    Cameron, F L
    Murray, C D
    Parkes, M
    Gooding, I
    Ahmad, Tariq
    Gaya, D R
    Mann, S
    Lindsay, J O
    Gordon, J
    Satsangi, J
    Hart, A
    McCartney, S
    Irving, P
    Lees, C W
    Date
    2016-02-19
    Journal
    Alimentary pharmacology & therapeutics
    Type
    Journal Article
    Meta-Analysis
    Systematic review
    Publisher
    Wiley
    DOI
    10.1111/apt.13547
    Rights
    Archived with thanks to Alimentary Pharmacology & Therapeutics. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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    Abstract
    Infliximab and adalimumab have established roles in inflammatory bowel disease (IBD) therapy. UK regulators mandate reassessment after 12 months' anti-TNF therapy for IBD, with consideration of treatment withdrawal. There is a need for more data to establish the relapse rates following treatment cessation.
    Citation
    Relapse after withdrawal from anti-TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta-analysis. 2016 Apr;43(8):910-923 Aliment. Pharmacol. Ther.
    Publisher URL
    http://dx.doi.org/10.1111/apt.13547
    Note
    This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.
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    • 2016 RD&E publications
    • Gastroenterology

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