Porcine dermis implants in soft-tissue reconstruction: current status
Author
Smart, Neil J.
Bryan, N.
Hunt, J. A.
Daniels, Ian R.
Date
2014-03-01Journal
Biologics : targets & therapyType
Journal ArticleReview
Publisher
Dove PressDOI
10.2147/BTT.S46469Metadata
Show full item recordAbstract
Soft-tissue reconstruction for a variety of surgical conditions, such as abdominal wall hernia or pelvic organ prolapse, remains a challenge. There are numerous meshes available that may be simply categorized as either synthetic or biologic. Within biologic meshes, porcine dermal meshes have come to dominate the market. This review examines the current evidence for their use and the limitations of knowledge. Although there is increasing evidence to support their safety, long-term follow-up studies that support their efficacy are lacking. Numerous clinical trials that remain ongoing may help elucidate their precise role in soft-tissue reconstruction.