Cancer Services
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Research outputs from Cancer Services at the RD&E.
Recent Submissions
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Republished: Immune checkpoint inhibitor induced large vessel vasculitis
(HighWire, 2021-02) -
Publisher Correction: The National Lung Matrix Trial of personalized therapy in lung cancer
(Nature Publishing Group, 2020-09)An amendment to this paper has been published and can be accessed via a link at the top of the paper. -
The National Lung Matrix Trial of personalized therapy in lung cancer
(Nature Publishing Group, 2020-07)The majority of targeted therapies for non-small-cell lung cancer (NSCLC) are directed against oncogenic drivers that are more prevalent in patients with light exposure to tobacco smoke1-3. As this group represents around ... -
Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer
(Atypon, 2020-10-01)Purpose: Previous studies of hypofractionated adjuvant whole-breast radiotherapy for early breast cancer established a 15- or 16-fraction (fr) regimen as standard. The FAST Trial (CRUKE/04/015) evaluated normal tissue ... -
British Gynaecological Cancer Society (BGCS) vulval cancer guidelines: Recommendations for practice
(Elsevier Science, 2020-09)The purpose of this guideline is to collate evidence and propose evidence-based guidelines for the diagnosis and management of adult patients with vulva carcinoma treated in the UK. Malignant melanoma may present via similar ... -
Immune checkpoint inhibitor induced large vessel vasculitis
(BMJ, 2020-05-18)This is a case report of a 67-year-old patient with castration resistant metastatic prostate cancer who developed an immune-mediated large vessel vasculitis following treatment with ipilimumab (anti-CTLA-4) and nivolumab ... -
Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic
(Elsevier Science, 2020-08)Patients treated with curative-intent lung radiotherapy are in the group at highest risk of severe complications and death from COVID-19. There is therefore an urgent need to reduce the risks associated with multiple ... -
Significance of a positive sentinel lymph node biopsy in staging for distant metastasis in breast cancer: are current guidelines relevant?
(Atypon, 2020-07)Introduction: In breast cancer, early identification of distant metastasis changes management. Current guidelines recommend radiological staging in patients with a preoperative positive axilla; no guidelines address a ...
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