• Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options 

  Ballard, Clive (IOS Press, 2019)

  Although Alzheimer's disease (AD) is the world's leading cause of dementia and the population of patients with AD continues to grow, no new therapies have been approved in more than a decade. Many clinical trials of ...

• The experiences of hospital staff who provide care for people living with dementia: A systematic review and synthesis of qualitative studies 

  Gwernan-Jones, R.; Abbott, R.; Rogers, M.; Green, C.; Ball, S.; Hemsley, Anthony; Cheeseman, Debbie; Moore, D. A.; Thompson Coon, J. (Wiley, 2020-05-15)

  Aims and objectives: To systematically review and synthesise qualitative data from studies exploring the experiences of hospital staff who care for people living with dementia (Plwd). Background: In hospital, the number ...

• APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort 

  Pilling, L. C.; Atkins, J. L.; Masoli, Jane A.; Delgado, J.; Melzer, David (Oxford University Press, 2020-05-26)

• Predicting incident delirium diagnoses using data from primary-care electronic health records 

  Bowman, K.; Jones, Lindsay; Masoli, Jane; Mujica-Mota, R.; Strain, David; Valderas, J. M.; Melzer, David; Delgado, J.; Butchart, Joseph (Oxford University Press, 2020-04-27)

  Importance: risk factors for delirium in hospital inpatients are well established, but less is known about whether delirium occurring in the community or during an emergency admission to hospital care might be predicted ...

• Challenges and practical recommendations for successfully recruiting inactive, statin-free older adults to clinical trials 

  Steele, A. M.; Libretto, Tina; Statton, Sarah A.; Etheridge, Timothy (BioMed Central, 2020-03-24)

  Objectives: To outline the challenges and provide practical recommendations for recruiting inactive, statin-free older adults to facilitate feasible study designs. Data was obtained from a double-blind randomised-controlled ...

• Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality 

  Masoli, Jane A.; Delgado, J.; Pilling, L. C.; Strain, David; Melzer, D. (Oxford University Press, 2020-08-24)

  Background: Blood pressure (BP) management in frail older people is challenging. An randomised controlled trial of largely non-frail older people found cardiovascular and mortality benefit with systolic (S) BP target <120 ...

• European Academy for medicine of ageing session participants' report on malnutrition assessment and diagnostic methods; an international survey 

  Hope, Suzy (Elsevier, 2020-02)

  Introduction: Malnutrition and nutrition-related diseases are associated with hospital admissions, disability, institutionalization, and mortality in older people. Specialists in Geriatric Medicine and nutrition evaluate ...

• The importance of different frailty domains in a population based sample in England 

  Sheridan, Ray (BioMed Central, 2020-01-15)

  Background: The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ...

• Developing an objective structured clinical examination in comprehensive geriatric assessment - a pilot study 

  Hemsley, Anthony (Wolters Kluwer, 2019-05)

  Acquiring medical competencies alone does not necessarily lead to the delivery of quality clinical care. Many UK training programs are soon to be based on the curricula of entrustable professional capabilities (EPCs). These ...

• Sarcopenia in acute care patients: protocol for the European Collaboration of Geriatric Surveys: Sarcopenia 9+ EAMA Project 

  Hope, Suzy (Elsevier, 2019-11)

• Association of blood pressure with clinical outcomes in older adults with chronic kidney disease 

  Masoli, Jane; Strain, W David (Oxford Academic, 2019-05)

  In chronic kidney disease (CKD), hypertension is associated with poor outcomes at ages <70 years. At older ages, this association is unclear. We tested 10-year mortality and cardiovascular outcomes by clinical systolic ...

• Home visits: A new screening tool for frailty? A retrospective exploratory study. 

  Jones, Lindsay (Academy of Family Physicians India, 2018-09)

  In the United Kingdom, the new NHS contract for primary care mandates that practices use the Electronic Frailty Index (EFI) to screen for frailty and apply clinical judgment, based on knowledge of the patient, to decide ...

• Clinical Outcomes of CADASIL-Associated NOTCH3 Mutations in 451,424 European Ancestry Community Volunteers. 

  Masoli, Jane A.; Pilling, L. C.; Kuchel, G. A.; Melzer, D. (Springer, 2018-10-18)

• Reply to Comments on: Proton Pump Inhibitors and Long-term Risk of Community-acquired Pneumonia in Older Adults. 

  Ble, A.; Zirk-Sadowski, J.; Masoli, Jane A. (Wiley, 2018-10-16)

• Antihypertensive medications may reduce the risk of dementia in older African–Americans with hypertension 

  Welsh, Tomas; Masoli, Jane (BMJ, 2018-09-25)

• Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts. 

  Atkins, J. L.; Delgado, J.; Pilling, L. C.; Bowman, K.; Masoli, Jane A.; Kuchel, G. A.; Ferrucci, L.; Melzer, D. (Oxford Journals, 2018-05-21)

  Individuals with low cardiovascular risk factor profiles experience lower rates of cardiovascular diseases, but associations with geriatric syndromes are unclear. We tested whether individuals with low cardiovascular disease ...

• Diabetes, cardiovascular disease and the microcirculation. 

  Strain, David; Paldánius, P M (BioMed Central, 2018-04-18)

  Cardiovascular disease (CVD) is the leading cause of mortality in people with type 2 diabetes mellitus (T2DM), yet a significant proportion of the disease burden cannot be accounted for by conventional cardiovascular risk ...

• Proton-Pump Inhibitors and Long-Term Risk of Community-Acquired Pneumonia in Older Adults. 

  Zirk-Sadowski, J.; Masoli, Jane A.; Delgado, J.; Hamilton, W. T.; Strain, David; Henley, W. E.; Melzer, D.; Ble, A. (Wiley, 2018-04-20)

  To estimate associations between long-term use of proton pump inhibitors (PPIs) and pneumonia incidence in older adults in primary care.

• Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative stakeholder initiative. 

  Strain, David; Hope, S V; Green, A; Kar, P; Valabhji, J; Sinclair, A J (Wiley, 2018-04-07)

  Rates of population ageing are unprecedented and this, combined with the progressive urbanization of lifestyles, has led to a dramatic shift in the epidemiology of diabetes towards old age, particularly to those aged 60-79 ...

• Intravascular lymphoma presenting with postural hypotension. 

  Pearce, Catharine; Hope, Suzy; Butchart, Joseph (BMJ, 2018-01-29)

  An 84-year-old woman presented with severe postural hypotension. Further assessment revealed weight loss, fatigue and fever at night. On examination, she had bilateral skin lesions on the inner thighs and skin biopsy ...

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