• EuGMS 2019 Congress report: evidence-based medicine in geriatrics 

  Hope, Suzy (PubMed Central, 2020-12)

  The 2019 EuGMS Congress "Evidence-Based Medicine in Geriatrics" was held in Krakow, Poland, and attended by over 1600 participants from 64 different countries. A summary and reflection on the congress was presented in the ...

• Drug repositioning and repurposing for Alzheimer disease 

  Ballard, Clive; Corbett, Anne (Nature Publishing Group, 2020-12)

  Drug repositioning and repurposing can enhance traditional drug development efforts and could accelerate the identification of new treatments for individuals with Alzheimer disease (AD) dementia and mild cognitive impairment. ...

• Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes 

  Ballard, Clive; Melzer, David; Jones, Lindsay; Delgado, J. (Oxford University Press, 2021-02-26)

  Importance: treatment of dementia in individuals with comorbidities is complex, leading to potentially inappropriate prescribing (PIP). The impact of PIP in this population is unknown. Objective: to estimate the rate ...

• The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease 

  Ballard, Clive (Elsevier Science, 2019-05)

  Objectives: To describe the incidence of delirium recording before and after a diagnosis of dementia is established in patients with dementia with Lewy bodies (DLB) and compare findings to a matched cohort of patients with ...

• Evaluating enhanced recovery after surgery: time to cover new ground and discover the missing patient voice 

  Nunns, M.; John, Joseph; McGrath, John S; Briscoe, S.; Thompson Coon, J.; Lovegrove, Chris; Thomas, David; Anderson, R. (BioMed Central, 2020-09-14)

  Multicomponent peri-operative interventions offer to accelerate patient recovery and improve cost-effectiveness. The recent National Institute of Health Research-commissioned evidence synthesis review by Nunns et al. ...

• An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene 

  Roubroeks, J.; Smith, Adam R.; Smith, R. G.; Pishva, Ehsan; Hannon, Eilis; Mill, Jonathan; Lunnon, Katie (Elsevier Science, 2020-11)

  A growing number of epigenome-wide association studies have demonstrated a role for DNA methylation in the brain in Alzheimer's disease. With the aim of exploring peripheral biomarker potential, we have examined DNA ...

• Dementia prevention, intervention, and care: 2020 report of the Lancet Commission 

  Ballard, Clive (Elsevier Science, 2020-08-08)

• Functional cognitive disorder: dementia's blind spot 

  Ballard, Clive (Oxford University Press, 2020-10-01)

  An increasing proportion of cognitive difficulties are recognized to have a functional cause, the chief clinical indicator of which is internal inconsistency. When these symptoms are impairing or distressing, and not better ...

• Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options 

  Ballard, Clive (IOS Press, 2019)

  Although Alzheimer's disease (AD) is the world's leading cause of dementia and the population of patients with AD continues to grow, no new therapies have been approved in more than a decade. Many clinical trials of ...

• The experiences of hospital staff who provide care for people living with dementia: A systematic review and synthesis of qualitative studies 

  Gwernan-Jones, R.; Abbott, R.; Rogers, M.; Green, C.; Ball, S.; Hemsley, Anthony; Cheeseman, Debbie; Moore, D. A.; Thompson Coon, J. (Wiley, 2020-05-15)

  Aims and objectives: To systematically review and synthesise qualitative data from studies exploring the experiences of hospital staff who care for people living with dementia (Plwd). Background: In hospital, the number ...

• APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort 

  Pilling, L. C.; Atkins, J. L.; Masoli, Jane A.; Delgado, J.; Melzer, David (Oxford University Press, 2020-05-26)

• Predicting incident delirium diagnoses using data from primary-care electronic health records 

  Bowman, K.; Jones, Lindsay; Masoli, Jane; Mujica-Mota, R.; Strain, David; Valderas, J. M.; Melzer, David; Delgado, J.; Butchart, Joseph (Oxford University Press, 2020-04-27)

  Importance: risk factors for delirium in hospital inpatients are well established, but less is known about whether delirium occurring in the community or during an emergency admission to hospital care might be predicted ...

• Challenges and practical recommendations for successfully recruiting inactive, statin-free older adults to clinical trials 

  Steele, A. M.; Libretto, Tina; Statton, Sarah A.; Etheridge, Timothy (BioMed Central, 2020-03-24)

  Objectives: To outline the challenges and provide practical recommendations for recruiting inactive, statin-free older adults to facilitate feasible study designs. Data was obtained from a double-blind randomised-controlled ...

• Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality 

  Masoli, Jane A.; Delgado, J.; Pilling, L. C.; Strain, David; Melzer, D. (Oxford University Press, 2020-08-24)

  Background: Blood pressure (BP) management in frail older people is challenging. An randomised controlled trial of largely non-frail older people found cardiovascular and mortality benefit with systolic (S) BP target <120 ...

• European Academy for medicine of ageing session participants' report on malnutrition assessment and diagnostic methods; an international survey 

  Hope, Suzy (Elsevier, 2020-02)

  Introduction: Malnutrition and nutrition-related diseases are associated with hospital admissions, disability, institutionalization, and mortality in older people. Specialists in Geriatric Medicine and nutrition evaluate ...

• The importance of different frailty domains in a population based sample in England 

  Sheridan, Ray (BioMed Central, 2020-01-15)

  Background: The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ...

• Developing an objective structured clinical examination in comprehensive geriatric assessment - a pilot study 

  Hemsley, Anthony (Wolters Kluwer, 2019-05)

  Acquiring medical competencies alone does not necessarily lead to the delivery of quality clinical care. Many UK training programs are soon to be based on the curricula of entrustable professional capabilities (EPCs). These ...

• Sarcopenia in acute care patients: protocol for the European Collaboration of Geriatric Surveys: Sarcopenia 9+ EAMA Project 

  Hope, Suzy (Elsevier, 2019-11)

• Association of blood pressure with clinical outcomes in older adults with chronic kidney disease 

  Masoli, Jane; Strain, W David (Oxford Academic, 2019-05)

  In chronic kidney disease (CKD), hypertension is associated with poor outcomes at ages <70 years. At older ages, this association is unclear. We tested 10-year mortality and cardiovascular outcomes by clinical systolic ...

• Home visits: A new screening tool for frailty? A retrospective exploratory study. 

  Jones, Lindsay (Academy of Family Physicians India, 2018-09)

  In the United Kingdom, the new NHS contract for primary care mandates that practices use the Electronic Frailty Index (EFI) to screen for frailty and apply clinical judgment, based on knowledge of the patient, to decide ...

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