• Intra-anal use of imiquimod: what is the clinical evidence? 

  Gkegkes, Ioannis D. (Sage, 2019-09)

  Imiquimod has been demonstrated to be rather effective in patients with anal as well as perianal high-grade squamous intraepithelial lesions (HSILs). Nevertheless, until now the intra-anal use of imiquimod has been considered ...

• A comment on Persistent fistula after anorectal abscess drainage: local experience of 11 years 

  Gkegkes, Ioannis (Wolters Kluwer, 2019-07)

• Incidence of and risk factors for stoma-site incisional herniation after reversal 

  Brook, Antonia; De Haes, Femke; Smart, Neil J.; Mansfield, Steve; Daniels, Ian R. (Wiley, 2019-05-07)

• Open versus laparoscopic mesh repair of primary unilateral uncomplicated inguinal hernia: a systematic review with meta-analysis and trial sequential analysis 

  Bullen, N; Massey, L H; Antoniou, Stavros; Smart, Neil J. (Springer, 2019-06-03)

  One standard repair technique for groin hernias does not exist. The objective of this study is to perform an update meta-analysis and trial sequential analysis to investigate if there is a difference in terms of recurrence ...

• In support of mesh for hernia repair 

  Daniels, Ian R.; Smart, Neil J. (Wiley, 2019-06)

• Addition of docetaxel to first-line long-term hormone therapy in prostate cancer (STAMPEDE): modelling to estimate long-term survival, quality-adjusted survival and cost-effectiveness 

  Srinivasan, Rajaguru (Elsevier, 2018-12)

  Results from large randomised controlled trials have shown that adding docetaxel to the standard of care (SOC) for men initiating hormone therapy for prostate cancer (PC) prolongs survival for those with metastatic disease ...

• Pharmacist-led, video-stimulated feedback to reduce prescribing errors in doctors-in-training: a mixed methods evaluation 

  Parker, Hazel; Farrell, Odran; Bethune, Rob; Hodgetts, Ali (British Pharmacological Society, 2019-07)

  AIM: To develop and evaluate a feasible, authentic pharmacist-led prescribing feedback intervention for doctors-in-training, to reduce prescribing errors. METHODS: This was a mixed methods study. Sixteen postgraduate ...

• Systematic review and meta-analysis of incisional hernia post-reversal of ileostomy 

  De Haes, Femke; Bullen, N L; Smart, Neil J.; Antoniou, Stavros (Springer, 2019-05-09)

  Incisional hernia following closure of loop ileostomy is a common problem. Assessment of the proportion of this complication is limited by small sample size and inconsistent reporting. The aim of this review was to provide ...

• Differences in outcome between patients readmitted to index vs non-index hospital trusts after colorectal resection 

  Smart, Neil J. (Wiley, 2019-05-07)

  This study aimed to determine differences in outcome between patients readmitted to index vs non-index trusts after major surgery.

• Single centre experience of bilateral gracilis flap perineal reconstruction following extra-levator abdominoperineal excision 

  Coelho, James A. J.; McDermott, Frank D.; Cameron, O; Smart, Neil J.; Watts, Andrew M.; Daniels, Ian R. (Wiley, 2019-04)

  A variety of tissue flaps have been described for the closure of perineal wounds following abdominoperineal excision of the rectum (APE) or exenteration for locally advanced/recurrent rectal cancer and salvage surgery for ...

• Introduction to clinical practice guidelines 

  Antoniou, Stavros A. (Springer, 2019-03)

  Clinical practice guidelines (CPGs) consist of recommendations developed to support specific clinical encounters. Their actionable messages intend to guide best practice. CPGs are distinct from clinical pathways. Beyond ...

• Intersphincteric resection: indications and outcome. 

  McDermott, Frank; Smart, Neil J. (Springer, 2019-03)

  Despite advances in the management of rectal cancer, surgery remains the mainstay of treatment with curative intent. The major advance in rectal cancer care was the standardization of surgical technique, total mesorectal ...

• Response to 'Clinical outcomes and inflammatory response to single-incision laparoscopic (SIL) colorectal surgery: a single-blinded randomized controlled pilot study'. 

  Macmillan, Alexandra; Massey, L; Lawday, Samuel; Bethune, Rob (Wiley, 2019-05)

• A survey on practices for parastomal hernia prevention and repair among ESCP surgeons 

  Smart, Neil J. (Springer, 2019-03)

• European association for endoscopic surgery (EAES) consensus statement on single-incision endoscopic surgery 

  Antoniou, Stavros (Springer, 2019-04)

  Laparoscopic surgery changed the management of numerous surgical conditions. It was associated with many advantages over open surgery, such as decreased postoperative pain, faster recovery, shorter hospital stay and excellent ...

• Short-term results after laparoscopic repair of giant hiatal hernias with pledgeted sutures: a retrospective analysis 

  Antoniou, Stavros A. (Springer, 2019-01-25)

  Forty-one patients who underwent laparoscopic 270° Toupet fundoplication with pledgeted sutured crura between September 2014 and April 2017 were evaluated with regard to recurrence of hiatal hernia at 3 months and 1 year ...

• Use of laparoscopic videos amongst surgical trainees in the United Kingdom. 

  Smart, Neil J.; McGrath, John S (Elsevier, 2018-11-09)

  Surgical trainers consider laparoscopic videos as a useful teaching aid to maximize trainees' learning and skill development given the backdrop of time constraints and productivity demands. Aim of this study is to assess ...

• Empowering junior doctors: a qualitative study of a QI programme in South West England 

  Bethune, Rob (BMJ, 2018-11-13)

  Aim: To explore how the South-West Foundation Doctor Quality Improvement programme affected foundation year 1 (F1) doctors’ attitudes and ability to implement change in healthcare. Methods Twenty-two ...

• Interactions Between Pseudomonas Immunotoxins and the Plasma Membrane: Implications for CAT-8015 Immunotoxin Therapy 

  Smart, Neil J.; Saunders, Sarah; Knight, Bridget A. (Frontiers in Oncology, 2018-11-08)

  Acute Lymphoblastic Leukaemia (ALL) remains the most frequent cause of cancer-related mortality in children and novel therapies are needed for the treatment of relapsed/refractory childhood ALL. One approach is the targeting ...

• Radiological progression of end colostomy trephine diameter and area 

  Smart, Neil J.; Daniels, Ian R. (BJS, 2018-10-24)

  Development of a parastomal hernia is common following abdominoperineal excision (APE). The true incidence is difficult to assess fully owing to differing lengths of follow-up and techniques used to assess herniation; ...

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