Ear, nose and throat (ENT)
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Research outputs from the ENT team at the RD&E.
Recent Submissions
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Ginkgo biloba for tinnitus
(Wiley, 2022-11-16)BACKGROUND: Tinnitus is a symptom defined as the perception of sound in the absence of an external source. In England alone there are an estimated ¾ million general practice consultations every year where the primary ... -
Denosumab and bisphosphonate associated bilateral osteonecrosis of the external auditory canal
(HighWire, 2022-08-25) -
Singing Exercises Improve Sleepiness and Frequency of Snoring among Snorers—A Randomised Controlled Trial
(Scientific Research Publishing, 2013-05-24)Objectives: To assess the effectiveness of regular singing exercises in reducing symptoms of snoring and sleep apnoea. Methods: A prospective single blinded randomised controlled trial was conducted in the otolaryngology ... -
A randomised controlled trial comparing Rapid Rhino Mannheim and Netcell series 5000 packs following routine nasal surgery
(European Rhinologic Society, 2009-04-23)OBJECTIVES: To determine whether there is a difference in discomfort between Netcell Series 5000 and Rapid Rhino Mannheim 8.0 cm (Cat. No. 800) packs used after routine nasal surgery, whilst in situ and during removal. ... -
The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial
(Elsevier, 2021-06-01)STUDY OBJECTIVE: Epistaxis is a common emergency department (ED) presentation and, if simple first aid measures fail, can lead to a need for anterior nasal packing. Tranexamic acid is an agent that contributes to blood ... -
Pleural malignant mesothelioma with metastatic deposition in the tongue
(BMJ, 2021-06-15)A 70-year-old man with epithelioid malignant pleural mesothelioma was referred to the maxillofacial surgery department with a painful lesion on the lateral border of his tongue which interfered with swallowing. Physical ... -
Denosumab and bisphosphonate associated bilateral osteonecrosis of the external auditory canal
(BMJ, 2021-06-15)We present a case of non-surgically managed bilateral osteonecrosis of the external auditory canal with a history of long-term medical therapy for osteoporosis. A 79-year-old woman with severe osteoporosis and destructive ... -
Understanding Factors That Cause Tinnitus: A Mendelian Randomization Study in the UK Biobank.
(Lippincott, Williams & Wilkins, 2021-06-08)OBJECTIVES: To investigate the causal role of established risk factors and associated conditions to tinnitus and tinnitus severity in the UK Biobank. DESIGN: The prospective cohort study with large dataset of >500,000 ... -
Familial bilateral nodular oncocytic hyperplasia of the parotid gland in mother and son.
(BMJ, 2021-04-19)This case series reports familial cases of nodular oncocytic hyperplasia (NOH) diagnosed in a mother and her son, 15 years apart. A 39-year-old man presented in 2003 with a lump below his left ear. Magnetic resonance imaging ... -
HCV infection and the risk of head and neck cancer: A meta-analysis
(Elsevier Science, 2020-06-26)Recent evidence has consistently suggested a role for HCV in the etiology of head and neck squamous cell carcinoma (HNSCC), but the conclusions of these studies have often been limited by small sample size. Therefore, a ... -
Isolated pituitary fossa metastasis from a primary tonsillar squamous cell carcinoma: case report
(Cambridge University Press, 2020-04)Objective: This paper presents a case of an isolated pituitary fossa metastasis on a background of a previously treated tonsillar squamous cell carcinoma. Case report: A 64-year-old male, diagnosed with a primary ... -
Beta human papillomaviruses infection and skin carcinogenesis
(Wiley, 2020-07)During the last decade, the worldwide incidence of keratinocyte carcinomas (KC) has increased significantly. They are now the most common malignancy, representing approximately 30% of all cancers. The role of ultraviolet ... -
Controversies in the surgical management of sporadic medullary thyroid carcinoma
(Wolters Kluwer, 2020-04)Purpose of review: Medullary thyroid carcinoma (MTC) represents a wide spectrum of tumours with differing biology, behaviour and natural history. The only current available curative treatment is surgery in the form of ... -
Predictive and prognostic significance of telomerase levels/telomere length in tissues and peripheral blood in head and neck squamous cell carcinoma.
(Nature, 2019-11)A growing body of evidence indicates that the expression of TERT, the catalytic subunit of telomerase, is a biological marker of progression in several cancers. We investigated the predictive and prognostic role of TERT ... -
The diagnostic value of cytology in Parotid Warthin's tumors: International Multicenter Series
(Wiley, 2020-03)Introduction: Warthin's tumor (WT) is a common benign salivary gland neoplasm with a negligible risk of malignant transformation. However, there is a risk of malignant tumors being misdiagnosed as WT on cytology and ... -
Association between Hepatitis C and B viruses and head and neck squamous cell carcinoma
(Elsevier, 2019-12)Hepatitis B and C viruses are known to be carcinogenic and have been associated with the development of non-Hodgkin's lymphoma as well as hepatocellular carcinoma. The incidence of head and neck cancer is increasing ... -
Surgical management of acquired anterior glottic web: a systematic review
(Cambridge Journals Online, 2019-09)Acquired anterior glottic web poses a significant challenge to laryngologists given its propensity to recur following treatment, and there are a wide variety of described techniques. -
The role of molecular genetics in the clinical management of sporadic medullary thyroid carcinoma: A systematic review
(Wiley, 2019-12)The significant variation in the clinical behaviour of sporadic medullary thyroid carcinoma (sMTC) causes uncertainty when planning the management of these patients. Several tumour genetic and epigenetic markers have been ...
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