Browsing 2015 RD&E publications by Author "Kalna, G."

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The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells

Munkley, J.; Livermore, K. E.; McClurg, U. L.; Kalna, G.; Knight, Bridget; McCullagh, Paul; McGrath, John S; Crundwell, Malcolm; Leung, H. Y.; Robson, C. N.; Harries, L. W.; Rajan, P.; Elliott, D. J. (Oncoscience, 2015-09-14)

Androgen receptor (AR) signalling and the PI3K pathway mediate survival signals in prostate cancer, and have been shown to regulate each other by reciprocal negative feedback, such that inhibition of one activates the ...