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Performance of mid infrared spectroscopy in skin cancer cell type identification
(SPIE, 2017-02-17)Marker free optical spectroscopy is a powerful tool for the rapid inspection of pathologically suspicious skin lesions and the non-invasive detection of early skin tumors. This goal can be reached by the combination of ... -
Mirrored stainless steel substrate provides improved signal for Raman spectroscopy of tissue and cells.
(Wiley, 2017-01)Raman spectroscopy (RS) is a powerful technique that permits the non-destructive chemical analysis of cells and tissues without the need for expensive and complex sample preparation. To date, samples have been routinely ... -
Assessment of Compressive Raman versus Hyperspectral Raman for Microcalcification Chemical Imaging
(American Chemical Society, 2018-05-15) -
Noninvasive Determination of Depth in Transmission Raman Spectroscopy in Turbid Media Based on Sample Differential Transmittance.
(American Chemical Society, 2017-09-19)Here we propose a simple noninvasive approach to determine the depth of a buried object using transmission Raman spectroscopy. In accordance with theory, the photons arising from spectral peaks that are suitably separated ... -
Determination of Depth in Transmission Raman Spectroscopy in Turbid Media Using a Beam Enhancing Element.
(Sage, 2017-08)This study demonstrates experimentally a method to enable prediction of depth of a chemical species buried in a turbid medium by using transmission Raman spectroscopy alone. The method allows the prediction of the depth ... -
Developing Raman spectroscopy as a diagnostic tool for label-free antigen detection.
(Wiley, 2017-07-12)For several decades, a multitude of studies have documented the ability of Raman spectroscopy (RS) to differentiate between tissue types and identify pathological changes to tissues in a range of diseases. Furthermore, ... -
High sensitivity non-invasive detection of calcifications deep inside biological tissue using Transmission Raman Spectroscopy.
(Wiley, 2017-06-21)The aim of this research was to develop a novel approach to probe non-invasively the composition of inorganic chemicals buried deep in large volume biological samples. The method is based on advanced Transmission Raman ... -
Multimodal registration of optical microscopic and infrared spectroscopic images from different tissue sections: An application to colon cancer
(Elsevier, 2017-09)Fourier transform infrared (FTIR) spectroscopic images provide rich information of the biochemical tissue composition that can be analyzed together with other microscopy modalities to perform objective pathological diagnoses. ... -
Discrimination of skin cancer cells using Fourier transform infrared spectroscopy.
(Elsevier, 2018-09-01)Fourier transform infrared (FTIR) spectroscopy is a highly versatile tool for cell and tissue analysis. Modern commercial FTIR microspectroscopes allow the acquisition of good-quality hyperspectral images from cytopathological ... -
Determination of inclusion depth in ex vivo animal tissues using surface enhanced deep Raman spectroscopy
(Wiley, 2020-01)This work presents recent developments in spatially offset and transmission Raman spectroscopy for noninvasive detection and depth prediction of a single SERS inclusion located deep inside ex vivo biological tissues. The ...