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    • Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients. 

      Iyengar, S S; Morgan-Hughes, G; Ukoumunne, O; Clayton, B; Davies, E J; Nikolaou, V; Hyde, C J; Shore, Angela; Roobottom, C A (Elsevier, 2016-02)
      To assess the diagnostic accuracy of computed tomography coronary angiography (CTCA) using a combination of high-definition CT (HD-CTCA) and high level of reader experience, with invasive coronary angiography (ICA) as the ...
    • Clinical effectiveness and cost-effectiveness of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) facilitated self-care rehabilitation intervention in heart failure patients and caregivers: rationale and protocol for a multicentre randomised controlled trial. 

      Taylor, R S; Hayward, C; Eyre, V; Austin, J; Davies, R; Doherty, P; Jolly, K; Wingham, J; Van Lingen, R; Abraham, C; Green, C; Warren, F C; Britten, Nicky; Greaves, C J; Singh, S; Buckingham, S; Paul, K; Dalal, H (BMJ, 2015-12-23)
      The Rehabilitation EnAblement in CHronic Heart Failure (REACH-HF) trial is part of a research programme designed to develop and evaluate a health professional facilitated, home-based, self-help rehabilitation intervention ...
    • Adherence to Oral Glucose-Lowering Therapies and Associations With 1-Year HbA1c: A Retrospective Cohort Analysis in a Large Primary Care Database. 

      Farmer, A; Rodgers, L; Lonergan, M; Shields, Beverley M; Weedon, M; Donnelly, L; Holman, R R; Pearson, E R; Hattersley, Andrew T. (American Diabetes Association, 2016-02)
      The impact of taking oral glucose-lowering medicines intermittently, rather than as recommended, is unclear. We conducted a retrospective cohort study using community-acquired U.K. clinical data (Clinical Practice Research ...
    • Maternal hypothyroxinaemia in pregnancy is associated with obesity and adverse maternal metabolic parameters. 

      Knight, Bridget A.; Shields, Beverley M; Hattersley, Andrew T.; Vaidya, Bijay (BioScientifica, 2016-01)
      Subclinical hypothyroidism and isolated hypothyroxinaemia in pregnancy have been associated with an increased risk of gestational diabetes. We aimed to ascertain if these women have a worse metabolic phenotype than euthyroid ...
    • Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. 

      Spiers, H; Hannon, Eilis; Wells, S; Williams, B; Fernandes, C; Mill, Jonathan (Elsevier, 2016-02-06)
      Epigenetic disruption has been implicated in many diseases of aging, and age-associated DNA methylation changes at specific genomic loci in humans are strongly correlated with chronological age. The aim of this study was ...
    • Whole exome sequence analysis reveals a homozygous mutation in PNPLA2 as the cause of severe dilated cardiomyopathy secondary to neutral lipid storage disease 

      Muggenthaler, Martina; Petropoulou, E.; Omer, S.; Simpson, M.A.; Sahak, H.; Rice, A.; Raju, H.; Conti, F.J.; Bridges, L.R.; Anderson, L.J.; Sharma, S.; Behr, E.R.; Jamshidi, Y. (Elsevier, 2016-02-13)
    • Measurement properties of multidimensional patient-reported outcome measures in neurodisability: a systematic review of evaluation studies. 

      Janssens, A.; Rogers, M.; Gumm, Rebecca; Jenkinson, C.; Tennant, A.; Logan, Stuart; Morris, Christopher (Wiley, 2015-12-11)
      To identify and appraise the quality of studies that primarily assessed the measurement properties of English language versions of multidimensional patient-reported outcome measures (PROMs) when evaluated with children ...
    • Tranexamic acid in major trauma: implementation and evaluation across South West England 

      Paudyal, P.; Smith, J.; Robinson, M.; South, A.; Higginson, I.; Reuben, Adam; Shaffee, J.; Black, S.; Logan, Stuart (Wolters Kluwer, 2015-08-26)
      OBJECTIVE: To carry out a prospective evaluation of tranexamic acid (TXA) use in trauma patients. PATIENTS AND METHODS: TXA was introduced to all emergency ambulances and emergency departments in the South West, UK, on 1 ...
    • A comparison of methods for EGFR mutation testing in non-small cell lung cancer. 

      Young, Elizabeth C.; Owens, Martina; Adebiyi, I; Bedenham, T; Butler, R; Callaway, J; Cranston, T; Crosby, C; Cree, I A; Dutton, L; Faulkes, C; Faulkner, C; Howard, E; Knight, J; Huang, Y; Lavender, L; Lazarou, L P; Liu, H; Mair, D; Milano, A; Sandell, S; Skinner, A; Wallace, A; Williams, M. V.; Spivey, V; Goodall, J; Frampton, J; Ellard, Sian (Wolters Kluwer, 2013-12)
      EGFR mutation testing of tumor samples is routinely performed to predict sensitivity to treatment with tyrosine kinase inhibitors for patients with non-small cell lung cancer. At least 9 different methodologies are employed ...
    • Hyaluronidase 2 deficiency is a molecular cause of cor triatriatum sinister in mice. 

      Chowdhury, B.; Xiang, B.; Muggenthaler, Martina; Dolinsky, V. W.; Triggs-Raine, B. (Elsevier, 2016-02-10)
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    AuthorHattersley, Andrew T. (75)Mill, Jonathan (55)Ellard, Sian (48)Stone, Nick (37)Shore, Angela (32)McDonald, Timothy J. (31)Flanagan, Sarah (30)Shepherd, Maggie (26)Crosby, Andrew H. (23)Ballard, Clive (22)... View MoreSubjectOncology. Pathology. (135)Endocrinology (107)Cardiology (21)Neurology (20)Clinical pathology (19)Paediatrics (18)Psychology (14)Mental health (12)Biochemistry (11)Eldery care. (8)... View MoreDate Issued2010 - 2020 (384)2000 - 2009 (7)Has File(s)
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