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Limbic encephalitis driven by a pleural mesothelioma: a paraneoplastic complication
(Middle East Journal of Cancer, 2016-10)Paraneoplastic neurological syndromes have only been described with pleural mesothelioma in five cases. We have described a 72-year-old man who developed anterograde amnesia 27 months after diagnosis of epithelioid pleural ... -
Touching the void - First and third person perspectives in two cases of autobiographical amnesia linked to temporal lobe epilepsy.
(Elsevier, 2018-02)Temporal lobe epilepsy (TLE) can be associated with a marked impairment of autobiographical memory. This is occasionally its presenting feature. We describe two individuals with severe epilepsy-associated autobiographical ... -
Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke.
(Elsevier, 2016-03-01)The grey-scale median of the common carotid artery intima-media complex (IM-GSM) characterizes arterial wall composition, and a low IM-GSM is associated with increased cardiovascular mortality in the elderly. We aimed to ... -
Reflections on aphantasia.
(Elsevier, 2016-01) -
The GABAB receptor agonist, baclofen, contributes to three distinct varieties of amnesia in the human brain - A detailed case report.
(Elsevier, 2016-01)We describe a patient in whom long-term, therapeutic infusion of the selective gamma-amino-butyric acid type B (GABAB) receptor agonist, baclofen, into the cerebrospinal fluid (CSF) gave rise to three distinct varieties ... -
Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia.
(Nature, 2016-12-19)Histone lysine methylation, mediated by mixed-lineage leukemia (MLL) proteins, is now known to be critical in the regulation of gene expression, genomic stability, cell cycle and nuclear architecture. Despite MLL proteins ... -
Commentary on: Implementing mechanical thrombectomy for acute ischaemic stroke in the UK.
(Elsevier, 2017-02)Stroke is the third leading cause of death and the leading cause of disability in the developed world.1 The treatment approach for acute ischaemic stroke is straightforward: restore blood flow as soon as possible and as ... -
Manipulation of oxygen and endoplasmic reticulum stress factors as possible interventions for treatment of multiple sclerosis: evidence for and against.
(Springer, 2017-01)Multiple sclerosis (MS) is normally considered a chronic inflammatory disease of the central nervous system (CNS), where T-cells breaching the blood brain barrier react against proteins of the axonal myelin sheaths, leading ... -
On Picturing a Candle: The Prehistory of Imagery Science.
(Frontiers In Psychology, 2016-04-07)The past 25 years have seen a rapid growth of knowledge about brain mechanisms involved in visual mental imagery. These advances have largely been made independently of the long history of philosophical - and even psychological ... -
Experiences of stroke survivors, their families and unpaid carers in goal setting within stroke rehabilitation: a systematic review of qualitative evidence.
(Wolters Kluwer, 2018-06)The objective of the review was to synthesize the best available qualitative evidence regarding the experiences of stroke survivors, their families and unpaid carers, about goal setting within stroke rehabilitation.