• Response to Comment on "ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank" by Kuo et al 

  Melzer, David (Oxford University Press, 2020-10-15)

• Are children with unrecognised psychiatric disorders being excluded from school? A secondary analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007 

  Logan, Stuart (Cambridge University Press, 2019-11)

  Background: There is limited research that explores the association between exclusion from school and mental health, but it seems intuitively plausible that the recognition of mental difficulties by key teachers and parents ...

• Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology 

  Lunnon, Katie (Wiley, 2020-09)

  Introduction: Abnormal gene expression patterns may contribute to the onset and progression of late-onset Alzheimer's disease (LOAD). Methods: We performed transcriptome-wide meta-analysis (N = 1440) of blood-based ...

• The mental and physical health profiles of older adults who endorse elevated autistic traits 

  Corbett, Anne; Ballard, Clive; Creese, Byron (Oxford University Press, 2020-08-05)

  Objective: The mental and physical health profile of autistic people has been studied in adolescence and adulthood, with elevated rates of most conditions being reported. However, this has been little studied taking a ...

• Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study 

  McDonald, Timothy J.; Jones, Angus (Elsevier Science, 2020-08)

  Background: Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing ...

• Guidelines on the use of irradiated blood components 

  Kerr, Paul (Wiley, 2020-12)

• Incisional hernia formation in hepatobiliary surgery using transverse and hybrid incisions: a systematic review and meta-analysis 

  Smith, Neil J. (Atypon, 2020-11)

  Introduction: Evidence suggests that midline incisions should be closed with the small-bite technique to reduce IH formation. No recommendations exist for the closure of transverse incisions used in hepatobiliary surgery. ...

• Periacetabular Osteotomy for Developmental Dysplasia of the Hip and Femoroacetabular Impingement: A Study Using the U.K. Non-Arthroplasty Hip Registry (NAHR) Data Set 

  Wilson, Matthew (Wolters Kluwer Health, Inc., 2020-08-05)

  Background: Periacetabular osteotomy (PAO) is a well-recognized procedure for the treatment of hip dysplasia in young adults and can be used for the surgical management of femoroacetabular impingement (FAI) with acetabular ...

• Pulse oximetry in low-resource settings during the COVID-19 pandemic 

  Wilson, Iain H. (Elsevier Science, 2020-09)

• Assessing performance of pathogenicity predictors using clinically relevant variant datasets 

  Gunning, Adam; Fasham, James; Crosby, Andrew H.; Ellard, Sian; Baple, Emma L.; Wright, Caroline F. (HighWire, 2020-08-25)

  Background: Pathogenicity predictors are integral to genomic variant interpretation but, despite their widespread usage, an independent validation of performance using a clinically relevant dataset has not been ...

• Precision Medicine in Type 2 Diabetes: Using Individualized Prediction Models to Optimize Selection of Treatment 

  Dennis, J. M. (HighWire, 2020-10)

  Despite the known heterogeneity of type 2 diabetes and variable response to glucose lowering medications, current evidence on optimal treatment is predominantly based on average effects in clinical trials rather than ...

• Letter: online search trends suggest patient concerns around immunosuppression use in inflammatory bowel disease during COVID-19 in the United Kingdom 

  Kennedy, Nicholas A. (PubMed Central, 2020-09)

• Meta-analysis of the demographic and prognostic significance of right-sided versus left-sided acute diverticulitis 

  Smart, Neil J. (Wiley, 2020-08-27)

  Aim: The aim of this work was to compare demographic factors, outcomes and prognosis for right-sided versus left-sided acute colonic diverticulitis. Method: We searched MEDLINE, CINAHL, EMBASE, CENTRAL, Scopus and ...

• British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease 

  Mitchelmore, Philip J. (BMJ, 2020-05)

• Risk of Anemia With Metformin Use in Type 2 Diabetes: A MASTERMIND Study 

  Dennis, J. M.; Hattersley, Andrew T. (HighWire, 2020-10)

  Objective: To evaluate the association between metformin use and anemia risk in type 2 diabetes, and the time-course for this, in a randomized controlled trial (RCT) and real-world population data. Research design and ...

• Real-world adherence, persistence, and in-class switching during use of dipeptidyl peptidase-4 inhibitors: a systematic review and meta-analysis involving 594,138 patients with type 2 diabetes 

  McGovern, Andrew (Springer, 2021-01)

  Aims: Medication adherence and persistence are important determinants of treatment success in type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis evaluated the real-world adherence, persistence, and ...

• Pathogenic germline variants in patients with features of hereditary renal cell carcinoma: Evidence for further locus heterogeneity 

  Castle, Bruce; Sansbury, Francis H (Wiley, 2021-01)

  Inherited renal cell carcinoma (RCC) is associated with multiple familial cancer syndromes but most individuals with features of non-syndromic inherited RCC do not harbor variants in the most commonly tested renal cancer ...

• Challenging infections in pregnancy 

  Morgan, Marina (PubMed Central, 2020-09)

  Maternal sepsis is "a life-threatening condition defined as organ dysfunction resulting from infection during pregnancy, childbirth, post-abortion, or postpartum period." (World Health Organisation, 2017). Serious infection ...

• Robotic Management of Fibroids: Discussion of Use, Criteria and Advantages 

  Gkegkes, Ioannis D. (Acta Medica, 2020)

  Fibroids are the most common benign tumors affecting fertility and quality of life. Different methods either definitive or fertility sparing are used for their management by using open, laparoscopic and robotic techniques. ...

• Nomogram Predicting Bladder Cancer-specific Mortality After Neoadjuvant Chemotherapy and Radical Cystectomy for Muscle-invasive Bladder Cancer: Results of an International Consortium 

  McGrath, John S; Aning, J. (Elsevier Science, 2020-08-05)

  Background: Cisplatin-based neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) is associated with improved overall and cancer-specific survival. The post-NAC pathological stage has previously been ...

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