• Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study 

  Duckworth, Anna; Gibbons, Michael A.; Beaumont, Robin N.; Wood, A. R.; Lunnon, Katie; Tyrrell, Jessica; Scotton, C. J. (Elsevier Science, 2021-03)

  Background: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease accounting for 1% of UK deaths. In the familial form of pulmonary fibrosis, causal genes have been identified in about 30% of cases, and a majority ...

• British Gynaecological Cancer Society (BGCS) cervical cancer guidelines: Recommendations for practice 

  Forrest, Jenny (Elsevier Science, 2021-01)

  Cervix cancer in many countries is declining and screening programmes and immunisation will reduce the incidence in the next few decades. This guideline attempts to cover management of invasive disease reflecting diagnosis ...

• Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease 

  Halpin, David M (Atypon, 2021-01-01)

  The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has raised many questions about the management of patients with chronic obstructive pulmonary disease (COPD) and whether modifications of their ...

• BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms 

  Ellard, Sian; Stals, Karen (Elsevier Science, 2020-12-03)

  SWI/SNF-related intellectual disability disorders (SSRIDDs) are rare neurodevelopmental disorders characterized by developmental disability, coarse facial features, and fifth digit/nail hypoplasia that are caused by ...

• Along came a spider: an unusual organism identified in a peritoneal dialysis patient, a case report and literature review 

  Carnall, Victoria Jane; Auckland, Cressida; Mulgrew, Christopher J. (Bio Med Central, 2020-11-11)

  Background: Peritoneal dialysis-associated peritonitis can uncommonly be caused by fungal infections. When they do present, they are associated with significant mortality and morbidity. We describe a case where a sample ...

• How are Chaplaincy Departments Responding Amidst the COVID-19 Pandemic? A Snapshot of UK Responses to a Questionnaire 

  Harrison, Simon; Scarle, Julia (Equinox Publishing Ltd, 2020-08)

  This is a brief reflection on how chaplaincy in the United Kingdom is responding “on the ground” to COVID-19. It is based on a short questionnaire responded to by 27 chaplaincy teams, who were providing ministry during ...

• Diagnosis and management of mild to moderate psoriasis 

  Frow, Helen (Wiley, 2020-09-04)

  Psoriasis is a common long-term inflammatory skin condition, which when mild or moderate in severity can be managed effectively with topical treatments and lifestyle advice. This article focuses on the management of mild ...

• Management and care of patients with vulval conditions 

  Cleverdon, Maria (The British Dermatological Nursing Group, 2020-09)

• The choice of treatments for varicose veins: A study in trade-offs 

  Campbell, Bruce (Atypon, 2020-10)

• Fifteen-minute consultation: Vulval soreness in the prepubertal girl 

  Chanchlani, Neil (HighWire, 2020-11-27)

• Long-term Follow-up of Glycemic and Neurological Outcomes in an International Series of Patients With Sulfonylurea-Treated ABCC8 Permanent Neonatal Diabetes 

  Bowman, Pamela; Shepherd, Maggie; Babiker, Tarig; Thomas, N. J.; De Franco, Elisa; Ellard, Sian; Flanagan, Sarah; Hattersley, Andrew T. (HighWire, 2021-01)

  Objective: ABCC8 mutations cause neonatal diabetes mellitus that can be transient (TNDM) or, less commonly, permanent (PNDM); ∼90% of individuals can be treated with oral sulfonylureas instead of insulin. Previous studies ...

• Root-cause analyses of missed opportunities for the diagnosis of colorectal cancer in patients with inflammatory bowel disease 

  Chee, Desmond; Hamilton, Benjamin; Heerasing, Neel; Hendy, Peter; Chanchlani, Neil; Lin, Simeng; Daniels, Ian R.; Silva, N.; Osborne, Melanie; Kennedy, Nicholas A.; Goodhand, James R.; Ahmad, Tariq (Wiley, 2021-01)

  Background: Colonoscopic surveillance in patients with inflammatory bowel disease (IBD) leads to earlier detection of colorectal cancer (CRC) and reduces CRC-associated mortality. However, it is limited by poor adherence ...

• Reply from Stephen J. Bailey, Paulo G. Gandra, Andrew M. Jones, Michael C. Hogan and Leonardo Nogueira 

  Bailey, S. J.; Jones, Andrew M. (Wiley, 2020-04)

• Implementing Remote Memory Clinics to Enhance Clinical Care During and After COVID-19 

  Ballard, Clive (Frontiers Media SA, 2020-09-18)

  Social isolation is likely to be recommended for older adults due to COVID-19, with ongoing reduced clinical contact suggested for this population. This has increased the need for remote memory clinics, we therefore review ...

• Comparison of oral glucose tolerance test and ambulatory glycaemic profiles in pregnant women in Uganda with gestational diabetes using the FreeStyle Libre flash glucose monitoring system 

  Jones, A. G. (BioMed Central, 2020-10-19)

  Background: The diagnosis of hyperglycaemia in sub-Saharan Africa (SSA) is challenging. Blood glucose levels obtained during oral glucose tolerance test (OGTT) may not reflect home glycaemic profiles. We compare OGTT results ...

• Sarcopenia and Variation in the Human Leukocyte Antigen Complex 

  Jones, Garan; Pilling, L. C.; Melzer, David (Oxford University Press, 2020-01-20)

  Background: Aging is characterized by chronic inflammation plus loss of muscle mass and strength, termed sarcopenia. Human leukocyte antigen (HLA) types are drivers of autoimmune disease, although with limited penetrance. ...

• Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism 

  Mill, Jonathan (Nature Publishing Group, 2020-09-25)

  Autism spectrum disorder (ASD) is a phenotypically and genetically heterogeneous neurodevelopmental disorder. Despite this heterogeneity, previous studies have shown patterns of molecular convergence in post-mortem brain ...

• Predictors of changes after reasoning training in healthy adults 

  Ballard, Clive; Corbett, Anne (Wiley, 2020-12)

  Objectives: To investigate predictors of performance changes and their time course in healthy older adults. Design: A post hoc analysis of a RCT investigating the effect of reasoning cognitive training (ReaCT) compared ...

• Effects of Purified Anthocyanins in People at Risk for Dementia: Study Protocol for a Phase II Randomized Controlled Trial 

  Ballard, Clive (Frontiers Media SA, 2020-09-02)

  Background: The number of people with dementia is increasing, with huge challenges for society and health-care systems. There are no disease-modifying therapies available. There is, therefore, an urgent need to identify ...

• Transcription-based drug repurposing for COVID-19 

  Ballard, Clive (Elsevier Science, 2020-12)

  We have utilised the transcriptional response of lung epithelial cells following infection by the original Severe Acute Respiratory Syndrome coronavirus (SARS) to identify repurposable drugs for COVID-19. Drugs best able ...

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