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The Effect of Tiotropium in Symptomatic Asthma Despite Low- to Medium-Dose Inhaled Corticosteroids: A Randomized Controlled Trial
(Elsevier, 2015-11-07)BACKGROUND: Tiotropium, a once-daily long-acting anticholinergic bronchodilator, has demonstrated efficacy in patients with asthma who were symptomatic despite treatment with medium- to high-dose inhaled corticosteroids ... -
Acute bronchodilator responses decline progressively over 4 years in patients with moderate to very severe COPD.
(BioMed Central, 2014-08-31)We previously reported a progressive decline in absolute responses of FEV1 and FVC to a near-maximal dose of 2 different short-acting bronchodilators over 4 years. Since varying host factors and the method of expressing ... -
Palliative Care for COPD: Signs of Progress, but Still a Long Way to Go.
(American Thoracic Society, 2018-06-11) -
The Effect of Incidental Consolidation on Management and Outcomes in COPD Exacerbations: Data from the European COPD Audit.
(PLoS One, 2015-07-27)There is controversy regarding the significance of radiological consolidation in the context of COPD exacerbation (eCOPD). While some studies into eCOPD exclude these cases, consolidation is a common feature of eCOPD ... -
South West Respiratory Network inhaler training project
(Mark Allen Group, 2015-03-02)Correct inhaler technique is essential for patients to get benefits from their therapy. Evidence shows that up to 90% of patients do not take their inhaler properly. A number of factors are associated with an increased ... -
Improving inhaler technique
(Mark Allen Group, 2015-01-02)Correct inhaler technique is essential for patients to get benefits from their therapy. The South West Respiratory Network formulated a project to develop and deliver an inhaler technique training programme for clinicians -
Effect of a single exacerbation on decline in lung function in COPD.
(Elsevier, 2017-07)COPD exacerbations are associated with accelerated lung function decline, but whether they are causal is unknown. We evaluated the effect of a single exacerbation on rate of lung function change using data from the 4-year ... -
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.
(AJRCCM, 2017-01-27)This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention of COPD (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: ... -
Understanding fear and anxiety in patients at the time of an exacerbation of chronic obstructive pulmonary disease: a qualitative study.
(Sage, 2015-12)To determine the importance of fear and anxiety at the time of an exacerbation of chronic obstructive pulmonary disease. To assess the influence of carers and health professionals on this fear and anxiety. -
A retrospective study of the impact of a telephone alert service (Healthy Outlook) on hospital admissions for patients with chronic obstructive pulmonary disease
(Nature, 2014-10-23)BACKGROUND: Healthy Outlook is a service delivered by the UK Met Office directly to patients with chronic obstructive pulmonary disease (COPD) that has been in place since 2006. Its objective is to reduce the severity and ...