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A review of national guidelines for management of COPD in Europe.
(European Respiratory Society, 2016-02)The quality of care can be improved by the development and implementation of evidence-based treatment guidelines. Different national guidelines for chronic obstructive pulmonary disease (COPD) exist in Europe and relevant ... -
Diagnosis, assessment, and phenotyping of COPD: beyond FEV1
(Dove Press, 2016-02-18)COPD is now widely recognized as a complex heterogeneous syndrome, having both pulmonary and extrapulmonary features. In clinical practice, the diagnosis of COPD is based on the presence of chronic airflow limitation, as ... -
Case finding for chronic obstructive pulmonary disease in people attending long-term condition clinics in primary care.
(Sage, 2016-04-12)Despite increased interest and awareness of chronic obstructive pulmonary disease (COPD), nearly half of the people with COPD remain undiagnosed. Inviting people at risk for screening is unlikely to be effective as many ... -
Why choose tiotropium for my patient? A comprehensive review of actions and outcomes versus other bronchodilators.
(Elsevier, 2017-07)Chronic obstructive pulmonary disease (COPD) and asthma are leading causes of morbidity and mortality. This narrative review provides an appraisal of the pharmacological and clinical characteristics of tiotropium in COPD ... -
The Effect of Tiotropium in Symptomatic Asthma Despite Low- to Medium-Dose Inhaled Corticosteroids: A Randomized Controlled Trial
(Elsevier, 2015-11-07)BACKGROUND: Tiotropium, a once-daily long-acting anticholinergic bronchodilator, has demonstrated efficacy in patients with asthma who were symptomatic despite treatment with medium- to high-dose inhaled corticosteroids ... -
Eligibility of real-life patients with COPD for inclusion in trials of inhaled long-acting bronchodilator therapy.
(BioMed Central, 2016-09-23)Management guidelines of chronic obstructive pulmonary disease (COPD) are mainly based on results of randomised controlled trials (RCTs), but some authors have suggested limited representativeness of patients included in ... -
Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease.
(American Thoracic Society, 2016-09-01)Clinical phenotyping is currently used to guide pharmacological treatment decisions in chronic obstructive pulmonary disease (COPD), a personalized approach to care. Precision medicine integrates biological (endotype) and ...