• Neuropsychological Assessment of mTBI in Adults 

  Yates, Philip J; Reuben, Adam (Springer, 2019-11)

  Mild traumatic brain injury (mTBI), comprising 70–80% of all TBIs, is the commonest form of TBI, representing those injuries deemed to be at the lower end of the severity spectrum. In the general population, mTBI may occur ...

• POSU: A pilot study looking into the feasibility, safety and efficacy of a post-operative surgical unit for high-risk patients 

  Baldwin, Matthew; McCormick, Bruce; Foale, Mark; Belete, Martha; Chen, Connie; Williams, Helen; Stark, David; Matthews, Ed (Sage, 2019-12)

  In this ambitious quality improvement project, we investigated the possibility of using operating theatre post-operative recovery ward to care for high-risk patients overnight.

• Mechanical thrombectomy for acute ischaemic stroke: challenges and opportunities 

  James, Martin (2019-11)

• Patterns of postmeal insulin secretion in individuals with sulfonylurea- treated KCNJ11 neonatal diabetes show predominance of non- KATP- channel pathways 

  Bowman, Pamela; McDonald, Timothy J; Knight, Bridget A; Flanagan, Sarah; Leveridge, Maria; Spaull, Steve R; Shields, Beverley M; Hammersley, Suzanne; Shepherd, Maggie; Andrews, Rob; Patel, Kashyap A; Hattersley, Andrew T. (BMJ, 2019-12)

  Insulin secretion in sulfonylurea-treated KCNJ11 permanent neonatal diabetes mellitus (PNDM) is thought to be mediated predominantly through amplifying non-KATP-channel pathways such as incretins. Affected individuals ...

• Cutaneous Leishmaniasis in a globetrotting explorer 

  Hunt, William (BMJ, 2019-12)

• A longitudinal study of epileptic seizures in Alzheimer's Disease 

  Zeman, Adam (Frontiers in Neurology, 2019-12)

  The prevalence of epileptic seizures is increased in patients in the clinical stages of Alzheimer's disease (AD) when compared to age-matched cognitively normal populations. In previously reported work from the Presentation ...

• Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review 

  Hemsley, Anthony; McGrath, John S.; Lovegrove, Chris J.; Thomas, David (National Institute of Health Research, 2019-12)

  Background: Elective older adult inpatient admissions are increasingly common. Older adults are at an elevated risk of adverse events in hospital, potentially increasing with lengthier hospital stay. Hospital-led ...

• Residual adrenal function in Autoimmune Addison’s Disease—effect of dual therapy with rituximab and depot tetracosactide 

  Vaidya, Bijay (Endocrine Society, 2020-04)

  In autoimmune Addison's disease (AAD), exogenous glucocorticoid (GC) therapy is an imperfect substitute for physiological GC secretion. Patients on long-term steroid replacement have increased morbidity, reduced life ...

• GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI 

  Hattersley, Andrew T. (American Association for the Advancement of Science, 2019-09)

  Early childhood growth patterns are associated with adult health, yet the genetic factors and the developmental stages involved are not fully understood. Here, we combine genome-wide association studies with modeling of ...

• Barriers to undertaking technical skills 

  Garwood, James (Wiley, 2020-04)

• Prediction algorithms: pitfalls in interpreting genetic variants of autosomal dominant monogenic diabetes 

  Ellard, Sian; Colcough, Kevin; Patel, Kashyap A; Hattersley, Andrew T. (American Society for Clinical Investigation, 2020-01)

• NMDA receptor antibody encephalitis presenting as Transient Epileptic Amnesia 

  Zeman, Adam (Elsevier, 2019-02)

  Transient Epileptic Amnesia (TEA) is a subtype of temporal lobe epilepsy, typically presenting in a person's early 60s, and of unknown aetiology. Encephalitis caused by antibodies to NMDA receptors (NMDARE) has not previously ...

• The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: The VIP2 Study 

  Boulanger, Carole (Springer, 2020-01)

  Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival after ICU ...

• Cost-effectiveness of once-daily single-inhaler triple therapy In COPD: The IMPACT Trial 

  Halpin, David M G (Dove Press, 2019-11)

  We assessed the cost-effectiveness of single-inhaler fluticasone furoate (FF)/umeclidinium (UMEC)/vilanterol (VI) versus FF/VI or UMEC/VI from a Canadian public healthcare perspective, incorporating data from the IMPACT ...

• Introducing the endotype concept to address the challenge of disease heterogeneity in Type 1 diabetes 

  Morgan, Noel G; Oram, Richard A (American Diabetes Association, 2020-01)

  The clinical diagnosis of new-onset type 1 diabetes has, for many years, been considered relatively straightforward. Recently, however, there is increasing awareness that within this single clinical phenotype exists ...

• Developing an objective structured clinical examination in comprehensive geriatric assessment - a pilot study 

  Hemsley, Anthony (Wolters Kluwer, 2019-05)

  Acquiring medical competencies alone does not necessarily lead to the delivery of quality clinical care. Many UK training programs are soon to be based on the curricula of entrustable professional capabilities (EPCs). These ...

• Clinical effectiveness of once-daily fluticasone furoate/umeclidinium/vilanterol in usual practice: the COPD INTREPID study design. 

  Halpin, David M G (European Respiratory Society, 2019-11)

  Effectiveness studies complement conventional randomised controlled trials by providing a holistic view of treatments in the setting of usual clinical practice. We present the protocol for the ongoing INTREPID (INvestigation ...

• Estimating the effectiveness and cost-effectiveness of establishing additional endovascular thrombectomy stroke centres in England: a discrete event simulation 

  James, Martin A. (Biomed Central, 2019-11)

  We have previously modelled that the optimal number of comprehensive stroke centres (CSC) providing endovascular thrombectomy (EVT) in England would be 30 (net 6 new centres). We now estimate the relative effectiveness and ...

• A service evaluation between 2 week wait (2WW) skin cancer referrals via Teledermatology and the standard face-to-face pathway at a teaching hospital 

  Hunt, William T N (Wiley, 2019-11)

• Training opportunities in thoracic ultrasound for respiratory trainees: are current guidelines practical? 

  Batalla-Duran, Elizabeth (BMJ, 2019-10)

  Respiratory trainees in the UK face challenges in meeting current Royal College of Radiologists (RCR) Level 1 training requirements for thoracic ultrasound (TUS) competence, specified as attending 'at least one session per ...

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