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    • Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress 

      Montaser, Hossam; Patel, Kashyap A.; Balboa, Diego; Ibrahim, Hazem; Lithovius, Väinö; Näätänen, Anna; Chandra, Vikash; Demir, Korcan; Acar, S.; Ben-Omran, Tawfeg; Colclough, Kevin; Locke, Jonathan M.; Wakeling, Matthew; Lindahl, Maria; Hattersley, Andrew T.; Saarimäki-Vire, Jonna; Otonkoski, Timo (American Diabetes Association, 2021-04-01)
      Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-resident protein that plays a crucial role in attenuating ER stress responses. Although MANF is indispensable for the survival and ...